Short-term Effects of Artificial Tears on Visual Performance in Normal Subjects

Ridder, William H.; LaMotte, James; Ngo, Linh Phong; Fermin, Joe

doi:10.1097/01.opx.0000162646.30666.e3

Cited by 34 publications

(20 citation statements)

References 12 publications

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“…Several clinical studies support the hypothesis that increased aberration as a result of a tear film disruption may reduce retinal image quality [5,6,7,8,9,10]. This fact is supported by the finding that instillation of artificial tears in dry eyes reduces the optical aberrations and increases the optical quality of the retinal images [11,12,13]. …”

Section: Introductionsupporting

confidence: 63%

“…Montes-Mico et al [5, 7] found that in normal eyes after a blink there is initially a fairly rapid decrease in the aberrations associated with the anterior surface of the tear film as the tear film stabilizes and becomes smoother, followed by a gradual increase as evaporation causes the tear film to become more irregular and to start to break up. There are studies that report improvements with the use of artificial tear solutions in the visual performance of patients with dry eye [11,12,13]. Eyes with abnormal tear film function have been found to show larger optical aberrations than normal eyes, because of the greater degree of irregularity in the tear film.…”

Section: Discussionmentioning

confidence: 99%

“…Wavefront analysis has demonstrated an increase in higher-order aberrations for patients with dry eye compared with normal subjects [33]. Many studies have shown a reduction in optical aberrations with the use of artificial tears and a more stable tear film will produce better visual acuity, contrast sensitivity and reduced glare disability [10,11,12,13]. …”

Section: Discussionmentioning

confidence: 99%

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The Effect of Lubricating Eye Drop Containing Hydroxypropyl Guar on Perimetry Results of Patients with Glaucoma and Trachomatous Dry Eye

Güzey¹,

Satici²,

Karaman³

et al. 2009

Ophthalmologica

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Purpose: To evaluate the effects of a mid-viscosity mucomimetic lubricant eye drop containing hydroxypropyl guar (HPG) as a gelling agent on computerized perimetry FASTPAC test results of primary open-angle glaucoma (POAG) patients with trachomatous dry eye. Methods: Both eyes of 33 patients with bilateral POAG and trachomatous dry eye were included in the study. They were treated with the same antiglaucomatous eye drop and underwent computerized perimetry. Before and after the treatment with lubricant eye drop (Systane™) for 8 weeks, tear function tests (Schirmer test with topical anesthesia, fluorescein staining and tear film break-up time) and FASTPAC test with computerized perimetry were performed. Pre- and posttreatment tear functions, visual field test global indices, reliability indices, test duration and numbers of depressed points in pattern deviation plots were compared. Results: We found significant improvements in tear function tests results, in computerized perimetry FASTPAC test indices, test duration and the number of depressed points in pattern deviation plots in the posttreatment evaluations. Conclusion: This study indicates that there was a benefit of mid-viscosity lubricant eye drop containing HPG treatment on computerized perimetry FASTPAC test performance in POAG subjects with trachomatous dry eye. We assume that the positive effect of this therapy is probably due to a better tear film stability, resulting in a higher optical quality of the repaired anterior corneal surface.

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Section: Introductionsupporting

confidence: 63%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

The Effect of Lubricating Eye Drop Containing Hydroxypropyl Guar on Perimetry Results of Patients with Glaucoma and Trachomatous Dry Eye

Güzey¹,

Satici²,

Karaman³

et al. 2009

Ophthalmologica

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“…48,49 Instillation of eye drops can cause alterations in the tear film, possibly inducing some temporal changes in optical quality. [50][51][52] Several previous studies have reported a short-term effect of artificial tear drops on corneal topographic data 16,53-57 and corneal or ocular HOAs 58-65 in normal and dry eyes. Certain artificial tear components may contribute to a transient decrease in optical quality after the instillation of artificial tears.…”

Section: Accommodationmentioning

confidence: 98%

Overview of Objective Methods for Assessing Dynamic Changes in Optical Quality

Koh

Higashiura

Maeda

2016

Eye &Amp; Contact Lens: Science &Amp; Clinical Practice

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Quality of vision has been emphasized in ophthalmologic clinical practice in recent years. The optical or visual performance of the human eye is not static and fluctuates over time. Considering the major origins of temporal fluctuations in optical or visual performance, quantitative assessment of the dynamic changes in the optical quality of the entire eye is important. This review provides an overview of the clinical application of the objective methods for assessing dynamic changes in optical quality, particularly those associated with accommodation, the precorneal tear film, the prelens tear film, and contact lens movement and fitting.

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“…8 Measures of visual quality after instillation of artificial tears have been concerned primarily with the negative impact of the tears immediately after instillation. 7,9 Studies measuring improvements in contrast sensitivity typically have tested subjects in a very short time period (e.g., 10 minutes or less). 6,10 Longer term (weeks) effects of artificial tear instillation have been studied, and improvements in contrast sensitivity noted.…”

mentioning

confidence: 99%