Short-Term Effects of Ambient Particles on Cardiovascular and Respiratory Mortality

Analitis, Antonis; Katsouyanni, Klea; Dimakopoulou, Konstantina; Samoli, Evangelia; Nikoloulopoulos, Aristidis K.; Petasakis, Yannis; Touloumi, Giota; Schwartz, Joel; Anderson, Hugh; Cambra, Koldo; Forastiére, Francesco; Zmirou, Denis; Vonk, Judith M.; Clancy, Luke; Kříž, B; Bobvos, János; Pekkanen, Juha

doi:10.1097/01.ede.0000199439.57655.6b

Cited by 298 publications

(172 citation statements)

References 24 publications

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“…162 Subsequent analysis of APHEA-2 data found PM-mortality effects with both cardiovascular and respiratory mortality (see Table 1). 163 Mortality associations with PM were also observed for nine French cities 164 and three Australian cities. 165 Two Asian multicity studies have reported daily mortality associations with measures of PM (see Table 1).…”

Section: Multicity Studies Of Short-term Exposure Andmentioning

confidence: 82%

Health Effects of Fine Particulate Air Pollution: Lines that Connect

Pope

Dockery²

2006

Journal of the Air & Waste Management Association

5,614

3,159

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Efforts to understand and mitigate the health effects of particulate matter (PM) air pollution have a rich and interesting history. This review focuses on six substantial lines of research that have been pursued since 1997 that have helped elucidate our understanding about the effects of PM on human health. There has been substantial progress in the evaluation of PM health effects at different time-scales of exposure and in the exploration of the shape of the concentration-response function. There has also been emerging evidence of PM-related cardiovascular health effects and growing knowledge regarding interconnected general pathophysiological pathways that link PM exposure with cardiopulmonary morbidity and mortality. Despite important gaps in scientific knowledge and continued reasons for some skepticism, a comprehensive evaluation of the research findings provides persuasive evidence that exposure to fine particulate air pollution has adverse effects on cardiopulmonary health. Although much of this research has been motivated by environmental public health policy, these results have important scientific, medical, and public health implications that are broader than debates over legally mandated air quality standards.

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Section: Multicity Studies Of Short-term Exposure Andmentioning

confidence: 82%

Health Effects of Fine Particulate Air Pollution: Lines that Connect

Pope

Dockery²

2006

Journal of the Air & Waste Management Association

5,614

3,159

View full text Add to dashboard Cite

show abstract

“…The findings in this study were consistent with the observations made by Analitis (2006), who found that an increase in PM 10 by 10 µg/m 3 (lag 0+1) was associated with increases of 0.76% in cardiovascular deaths and 0.58% in respiratory deaths. Analitis et al applied a two-stage hierarchical modeling approach assessing city-specific effects first and then overall effects using the one-day moving average of current and posterior day concentrations of particles (lag = 01) [21].…”

Section: Discussionmentioning

confidence: 99%

Air Pollution Associated with Sumatran Forest Fires and Mortality on the Malay Peninsula

2017

Pol. J. Environ. Stud.

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The 2005 Malaysian haze was a week-long choking smog-like haze over Malaysia that almost brought the central part of peninsular Malaysia to a standstill and prompted crisis talks with Indonesia [1]. Lingering smoke from forest fires on the Indonesian island of Sumatra were identified as the primary cause. Farmers regularly burn scrub and forest to clear land during the dry season for agricultural purposes, but this was the worst haze that to hit Malaysia since the 1977 haze, when the daily average Pol. J. Environ. Stud. Vol. 26, No. 1 (2017)

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“…Large time series analyses have been conducted in North America and Europe to estimate the acute health risk of PM exposure. 4,5 It was found that coarse PM levels measured on a daily basis were significantly associated with short-term increases in mortality on individual days, particularly with cardiopulmonary mortality (Table 2). However, risk increases were relatively small and did not exceed beyond 1%.…”

Section: Particulate Matter and Human Health Particulate Matter Is A mentioning

confidence: 99%

Impact of Particulate Matter Exposition on the Risk of Ischemic Stroke: Epidemiologic Evidence and Putative Mechanisms

Bornstädt

Kunz

Endres

2013

J Cereb Blood Flow Metab

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Ambient particulate matter (PM) pollution is estimated to be responsible for 3.2 million deaths annually worldwide. Although many studies have demonstrated PM as a serious risk factor for cardiovascular diseases, less is known on its association with cerebrovascular events. Over the last decade, however, an increasing number of studies have provided data showing a relationship between PM exposure and ischemic stroke (IS). In this article, we will report on existing epidemiologic findings for an association between PM exposure and IS based on a systemic literature search. Thus, despite inconsistencies in the results, currently available data suggest that PM exposure is a risk factor for IS, especially in patients with preexisting illnesses. With regards to the mechanisms leading to PM-dependent vascular damage, in particular proinflammatory, prooxidative, as well as proatherogenic pathways have been suggested to be involved. Notably, to date there is only one study published, which demonstrates the influence of PM exposure on cerebrovascular function. We will discuss reasonable approaches for future neurovascular research in this field.

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Short-Term Effects of Ambient Particles on Cardiovascular and Respiratory Mortality

Abstract: These effect estimates are appropriate for health impact assessment and standard-setting procedures.

Cited by 298 publications

References 24 publications

Health Effects of Fine Particulate Air Pollution: Lines that Connect

Health Effects of Fine Particulate Air Pollution: Lines that Connect

Air Pollution Associated with Sumatran Forest Fires and Mortality on the Malay Peninsula

Impact of Particulate Matter Exposition on the Risk of Ischemic Stroke: Epidemiologic Evidence and Putative Mechanisms

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