2011
DOI: 10.1038/eye.2011.119
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Short-term changes in the optic nerve head and visual field after trabeculectomy

Abstract: Aims or Purpose To evaluate short-term changes in optic nerve head topography and visual field induced by surgical reduction of intraocular pressure. Methods A prospective study was performed on 56 eyes of 56 patients with uncontrolled primary open-angle glaucoma despite maximum medical therapy, which underwent trabeculectomy. Optic nerve head evaluations by means of Heidelberg Retina Tomograph, and visual field tests were performed pre-operatively, and at 3 and 6 months after surgery. Differences in intraocul… Show more

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Cited by 13 publications
(8 citation statements)
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References 27 publications
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“…Anterior displacement of the ONH surface resulting from acute reduction in IOP has been observed in adult glaucoma patients undergoing trabeculectomy [12][13][14][15][16][17] and in a subset of patients with a large IOP reduction after medical treatment. 18,19 Because these studies used CSLT in which the ALS cannot be visualized, the source of ONH surface changes cannot be precisely elucidated.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Anterior displacement of the ONH surface resulting from acute reduction in IOP has been observed in adult glaucoma patients undergoing trabeculectomy [12][13][14][15][16][17] and in a subset of patients with a large IOP reduction after medical treatment. 18,19 Because these studies used CSLT in which the ALS cannot be visualized, the source of ONH surface changes cannot be precisely elucidated.…”
Section: Discussionmentioning
confidence: 99%
“…10,11 Several studies have examined ONH surface changes with confocal scanning laser tomography (CSLT) after surgical [12][13][14][15][16][17] or medical 18,19 reduction of IOP. However, because CSLT is able to image only ONH surface changes, none of these earlier studies were able to evaluate the contribution of deep ONH structures resulting in the increase of neuroretinal rim area and decrease of optic disc cupping after IOP reduction.…”
mentioning
confidence: 99%
“…We tried to overcome method limitations by using largely validated operating procedures to record the 24-hour IOP curves which have been reported in previous publications [6,17,18,19,20,21,22,23]. The operators at each site were well trained and had shown a high degree of concordance at the beginning of the study.…”
Section: Discussionmentioning
confidence: 99%
“…IOP reduction also reduces the effects of the disease on the visual field and optic nerve head [6,7], and as a consequence also the effects of IOP-lowering treatments need to be monitored over time.…”
Section: Introductionmentioning
confidence: 99%
“…3,4 Several risk factors for progression of visual field loss have been identified, including abnormal baseline anticardiolipin antibody levels, older age, raised intraocular pressure (IOP), and female sex. 5 Nevertheless, the only modifiable risk factor for the glaucoma progression is currently IOP.…”
Section: Introductionmentioning
confidence: 99%