Short-Term Change of Exercise Capacity in Patients with Pulmonary Valve Replacement after Tetralogy of Fallot Repair

Hwang, Tae-Yeon; Kim, Sung Ook; Kim, Moon Sun; Jang, So Ick; Kim, Seong Ho; Lee, Sang-Yun; Choi, Eun Young; Park, Su Jin; Kwon, Hye Won; Lim, Hyo Bin

doi:10.4070/kcj.2016.0226

Cited by 5 publications

(2 citation statements)

References 28 publications

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“…Moreover, Roderick et al found that prolonged QRS duration prior to PVR is the main determinant of the poor long-term follow-up outcome of patients with ToF ( 32 ); however, our study did not find such a result. Some studies found that VO 2 peak (%), which assesses the degree of exercise tolerance, may be a useful predictor of adverse events after PVR ( 33 , 34 ). Although we were not able to obtain the results of the cardiopulmonary exercise experiment, we also concluded that patients with NYHA III/IV have a poor prognosis based on the NYHA classification, which correlates with the study conducted by Anna et al ( 35 ).…”

Section: Discussionmentioning

confidence: 99%

Left ventricular strain derived from cardiac magnetic resonance can predict outcomes of pulmonary valve replacement in patients with repaired tetralogy of Fallot

Zhuang

Feng

et al. 2022

Front. Cardiovasc. Med.

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PurposeSeveral adults with repaired tetralogy of Fallot (rToF) undergo pulmonary valve replacement (PVR) to reduce the right ventricular volume and retain right ventricular function. However, there is currently no consensus on the ideal time for PVR surgery in asymptomatic patients with rTOF with pulmonary regurgitation (PR). Clinical outcomes after PVR are also indeterminate. Recently, myocardial strain and strain rate derived from cardiac magnetic resonance (CMR) feature tracking were found to be more sensitive to right ventricular dysfunction than conventional parameters and therefore may add prognostic value in patients with rToF. We aimed to analyze whether pre-PVR left ventricular (LV) strain and strain rate detected by CMR feature tracking are associated with midterm outcomes after PVR in patients with rToF.MethodsSeventy-eight asymptomatic patients with rToF who required PVR due to moderate or severe PR were prospectively enrolled between January 2014 and June 2020. CMR cine sequences were obtained, and feature tracking parameters were measured preoperatively. Adverse events were documented during the follow-up. Receiver operating characteristic analysis was performed to determine the cutoff value. Kaplan–Meier curves were drawn with log-rank statistics; moreover, univariate and multivariate Cox proportional hazards regression analyses and Harrel C-indices were analyzed.ResultsDuring 3.6 ± 1.8 years of follow-up, 25 adverse events were recorded. Kaplan–Meier survival curves and univariate Cox analysis verified that patients with significantly reduced radial strain (RS), circumferential strain (CS), longitudinal strain (LS), RS rate at systole and diastole (RSRs and RSRe), and circumferential and LS rates at diastole (CSRe and LSRe) had worse event-free survival. After multivariate correction, only LS and LSRe remained significantly associated with adverse outcomes (hazard ratio = 1.243 [1.083–1.428] and 0.067 [0.017–0.258], respectively, all p < 0.05). The cutoff values of LS and LSRe were −12.30 (%) and 1.07 (s–1), respectively.ConclusionThe LV strain and strain rate prior to PVR are important prognostic factors for adverse events after PVR in rToF.

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Section: Discussionmentioning

confidence: 99%

Left ventricular strain derived from cardiac magnetic resonance can predict outcomes of pulmonary valve replacement in patients with repaired tetralogy of Fallot

Zhuang

Feng

et al. 2022

Front. Cardiovasc. Med.

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“…Maximal oxygen uptake (VO 2 max) is a useful index for the assessment of exercise capacity, as it can powerfully predict outcomes of cardiac and pulmonary disorders. 2 3 4 5 6 7 VO 2 max can be directly measured by CPET. Exercise capacity indicated by VO 2 max can help in estimating cardiopulmonary risk, thus making the selection of normal reference value essential for interpretation.…”

Section: Introductionmentioning

confidence: 99%

Comparison of Predicted Exercise Capacity Equations in Adult Korean Subjects

Jeong

Lee

et al. 2022

J Korean Med Sci

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Background Maximal oxygen uptake (VO 2 max) is a useful index to assess exercise capacity. However, there is no reference value for Koreans. This study aimed to compare actual VO 2 max and predicted VO 2 max using exercise capacity equations in Korean subjects. Methods This retrospective study enrolled 383 patients who underwent cardiopulmonary exercise test (CPET) with incremental maximal cycle ergometer test at Asan Medical Center from January 2020 to May 2021. Stage 1 and 2 lung cancer patients with normal lung function and healthy persons of 50 subjects who had maximal CPET were analyzed. Results The subjects were aged 65 ± 13 years and predominantly male (74%). CPET results were as follows: absolute VO 2 max, 1.2 ± 0.3 L/min; body weight referenced VO 2 max, 20 ± 3.9 mL/kg/min; peak work rate, 94 ± 24 watts; peak heart rate, 142 ± 21 bpm; peak O 2 pulse, 10 ± 3 mL/beat; minute ventilation, 59 ± 14 L/min; peak respiratory rate, 34 ± 6 breaths per minute; and peak breathing reserve, 41 ± 18%. There was significant discordance between the measured and predicted absolute VO 2 max using the Jones, Hansen, and Wasserman prediction equations developed for Caucasian population ( P < 0.001). Agreement using Bland-Altman test between true and predicted absolute VO 2 max was the best in Chinese equation (−0.03, 2SD = 0.55) compared to Jones (0.42, 2SD = 1.07), Hansen (0.44, 2SD = 0.86), and Wasserman (0.42, 2SD = 0.86) equations. Conclusion The reference value and prediction equation from studies including primarily Caucasians may not be appropriate for Koreans. Since the mean difference is the lowest in Chinese equation, the Chinese equation might be used for the Korean adult population.

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Repair of tricuspid valve with pulmonary valve replacement in repaired tetralogy of fallot

Kim

Song

Kim

et al. 2019

Scandinavian Cardiovascular Journal

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Short-Term Change of Exercise Capacity in Patients with Pulmonary Valve Replacement after Tetralogy of Fallot Repair

Cited by 5 publications

References 28 publications

Left ventricular strain derived from cardiac magnetic resonance can predict outcomes of pulmonary valve replacement in patients with repaired tetralogy of Fallot

Left ventricular strain derived from cardiac magnetic resonance can predict outcomes of pulmonary valve replacement in patients with repaired tetralogy of Fallot

Comparison of Predicted Exercise Capacity Equations in Adult Korean Subjects

Repair of tricuspid valve with pulmonary valve replacement in repaired tetralogy of fallot

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