Short-term association between ambient air pollution and pneumonia in children: A systematic review and meta-analysis of time-series and case-crossover studies

Nhung, Nguyễn Thị Trang; Amini, Heresh; Schindler, Christian; Joss, Meltem Kutlar; Dien, Tran Minh; Probst‐Hensch, Nicole; Pérez, Laura; Künzli, Nino

doi:10.1016/j.envpol.2017.07.063

Cited by 227 publications

(156 citation statements)

References 49 publications

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“…Earlier evidence indicated that the small particles can reach bronchioles and penetrate up to the primary, secondary terminal bronchi, and alveoli in the lung which may trigger mucous secretions in airways, reduce air flow and then cause wheezing (54,55). Although previous studies reported significant effects of PM 10 on respiratory diseases in children (27,52,56), the effects on wheeze-associated disorders was not clear. We found significant associations in some sensitivity analyses but those results were based on removing a large study or including lower quality score studies into meta-analysis so we concluded that further studies were needed to clarify this association.…”

Section: Discussionmentioning

confidence: 98%

“…Each single city in a multi-city study and each sub-group defined by age, diagnosis, health outcome or season was included one by one as an independent study. The pooled effect sizes were computed for every single lag and cumulative lag provided in individual studies for each air pollutant separately if at least three individual estimates were available (27,36).…”

Section: Data Synthesismentioning

confidence: 99%

“…Seven out of 10 studies included in this review were carried out in low-income countries whose children may suffer larger risks of respiratory admission (27,73,74). This is because children living in low-and middle-income countries might not only experience higher exposure to ambient air pollution but also be exposed to additional risk factors for respiratory diseases, wheeze-associated disorders, such as smoke from biomass burning at home, a large fraction of the population continues to use tobacco products in the home, or poor diets that may amplify the effects of ambient air pollution (28,56,75).…”

Section: Figure 2: (Continued)mentioning

confidence: 99%

“…Finally, our meta-analysis is based on different designs of observational studies from cross-sectional, cohort, panel to case-crossover and time-series. Therefore, individual studies may be influenced by uncontrolled time-varying biases which we could not examine (27,39,48).…”

Section: Limitationsmentioning

confidence: 99%

“…Ambient air pollution has been associated with increased respiratory morbidity and mortality, however, few studies have been carried out in Southeast Asia, where people are exposed to much higher levels of air pollution and might experience the greatest burden of diseases due to wheeze-associated diseases/disorders (26). Several systematic reviews have been conducted to examine the effect of air pollution on respiratory diseases in children, but there has not been a corresponding meta-analysis to estimate the effect sizes for wheeze-associated diseases/ disorders in Southeast Asian countries (27,28). Wheezing is a high-pitched whistling sound made while breathing out and may be a symptom of a serious lung disease such as acute lower respiratory infection, asthma or other wheeze-associated disorders.…”

Section: Introductionmentioning

confidence: 99%

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Impact of ambient air pollution and wheeze-associated disorders in children in Southeast Asia: a systematic review and meta-analysis

Luong

Sly

Thai

et al. 2019

Reviews on Environmental Health

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Abstract Several systematic reviews have been conducted so far to examine the effect of air pollution on respiratory diseases, but there has not been a corresponding meta-analysis to estimate the effect sizes for wheeze-associated diseases/disorders, which is one of the leading causes of emergency department visits and hospitalizations for children worldwide. The aim of this review is to systematically evaluate the relationship between air pollution and risk of wheeze-associated disorders in children in Southeast Asia. We searched the relevant computerized databases (PubMed, EMBASE, Web of Science, Scopus and Cochrane library) for indexed publications up to July 2018. Finally, eight studies were qualified for performing a random-effect meta-analysis to compute the pooled effect sizes. The results show that each increase of 10 μg/m3 in concentrations of PM2.5, PM1 was associated with 1–2% increase in risk of wheeze-associated disorders. Positive associations were found for PM10, SO2, NO2, NOx but no association was found for CO and O3. We confirmed the strong effect of fine particulate matters on respiratory health and recommend an updated meta-analysis should be done when more studies are available.

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Section: Discussionmentioning

confidence: 98%

Section: Data Synthesismentioning

confidence: 99%

Section: Figure 2: (Continued)mentioning

confidence: 99%

Section: Limitationsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Impact of ambient air pollution and wheeze-associated disorders in children in Southeast Asia: a systematic review and meta-analysis

Luong

Sly

Thai

et al. 2019

Reviews on Environmental Health

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Quantification of the Cost and Potential Environmental Effects of Unused Pharmaceutical Products in Cataract Surgery

et al. 2019

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IMPORTANCE Pharmaceutical products, including unused portions, may contribute to financial and environmental costs in the United States. Because cataract surgery is performed millions of times each year in the United States and throughout the rest of the world, understanding these financial and environmental costs associated with cataract surgery is warranted. OBJECTIVE To investigate the financial and environmental costs of unused pharmaceutical products after phacoemulsification surgery. DESIGN, SETTING, AND PARTICIPANTS This descriptive qualitative study included 4 surgical sites in the northeastern United States (a private ambulatory care center, private tertiary care center, private outpatient center, and federally run medical center for veterans). Prices and data for use of services and pharmaceuticals were obtained for the tertiary care and outpatient centers from

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Excess prenatal loss and respiratory illnesses of infant macaques living outdoors and exposed to wildfire smoke

Berns,

Haertel

2024

American J Primatol

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Global climate change has transformed predictions of fire seasons in the near future, and record‐breaking wildfire events have had catastrophic consequences in recent years. In September 2020, multiple wildfires subjected Oregon to hazardous air quality for several days. In this retrospective cohort study, we aimed to examine prenatal loss, morbidity, and mortality of rhesus (Macaca mulatta) and Japanese macaques (Macaca fuscata) exposed to poor air quality from the nearby wildfires. Detailed medical records from 2014 to 2020 of 580 macaques housed outdoors at a research facility in Beaverton, Oregon were used to evaluate the association between these health outcomes and wildfire smoke exposure. Logistic regression models estimated excess prenatal loss, hospitalization rates, respiratory problems, and mortality during and following the wildfire event, and Kruskal–Wallis statistics were used to determine if infant growth was affected by wildfire smoke exposure. Risk of pregnancy loss (relative risk = 4.1; p < 0.001) and odds of diagnosis with a respiratory problem (odds ratio = 4.47; p = 0.003) were higher in exposed infant macaques compared to nonexposed infants. Infant growth was not affected by poor air quality exposure. Our findings suggest wildfire smoke exposure poses a risk to the health of infants and pregnant individuals and should be monitored more closely in the future.

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Short-term association between ambient air pollution and pneumonia in children: A systematic review and meta-analysis of time-series and case-crossover studies

Cited by 227 publications

References 49 publications

Impact of ambient air pollution and wheeze-associated disorders in children in Southeast Asia: a systematic review and meta-analysis

Impact of ambient air pollution and wheeze-associated disorders in children in Southeast Asia: a systematic review and meta-analysis

Quantification of the Cost and Potential Environmental Effects of Unused Pharmaceutical Products in Cataract Surgery

Excess prenatal loss and respiratory illnesses of infant macaques living outdoors and exposed to wildfire smoke

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