Short–term antimicrobial therapy–a pilot compliance study using ampicillin in dogs

Bomzon, L.

doi:10.1111/j.1748-5827.1978.tb05559.x

Cited by 17 publications

(14 citation statements)

References 2 publications

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“…Studies 41,42 involving owner compliance in veterinary medicine have investigated short-term use of antimicrobials and suggested that compliance is a problem. An important determinant for adherence was that animal owners felt that the veterinarians spent enough time during the consultation.…”

Section: Patient Health-a Reviewmentioning

confidence: 99%

What can veterinarians learn from studies of physician-patient communication about veterinarian-client-patient communication?

Shaw¹,

Adams²,

Bonnett³

2004

javma

115

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T he importance of communication skills in veterinary medicine is an emerging topic. For instance, 1 of the 6 critical issues identified during focus-group sessions of the KPMG study 1 was that "while the scientific, technical, and clinical skills of the veterinary profession remain high, there is evidence that veterinarians lack management and communication skills necessary for success in private practice." These are general findings and may not be reflective of the skills of all veterinarians. However, many veterinarians participating in that study reported that they did not receive sufficient training in communication skills. When the researchers asked pet owners to rate the most important factors in choosing a veterinarian, the 2 factors most commonly listed were that the veterinarian is kind and gentle and that the veterinarian is respectful and informative. It is apparent, therefore, that pet owners value the interpersonal skills of their veterinarians but that many veterinarians perceive that they are lacking these valuable skills.Over the past decade, veterinarians have witnessed substantial changes in the profession. One of the major changes is the increasing recognition of the relationships that people may have with their companion animals. 2 When asked about their relationship with their pets, 85% of pet owners reported that they viewed their pets as family members. 1 In conjunction with this, there is a growing recognition that provision of veterinary services in a manner that acknowledges the human-animal bond will lead to better outcomes for veterinary practices and their patients. 1 Appreciating the impact of animal companionship on the health and well-being of humans creates a new dimension for veterinarians in public health. Veterinarians' responsibilities have expanded to include the mental health and well-being of their clients, as well as their clients' pets. 2 In a recent address, Blackwell 2 stated that today' s veterinarians are faced with educated clients armed with questions and greater expectations. Veterinarians' responsibilities for addressing questions and providing client education are increased. In an increasingly litigious society, consumers are not forgiving of unprofessional services. 2 Most complaints to regulatory bodies are related to poor communication and deficient interpersonal skills, 3 with breakdowns in communication being a major cause of client dissatisfaction. In addition, it has been predicted that by the year 2005, women will become the majority in the veterinary profession, 4 and in a recent essay, Rucker 5 stated that women judge job satisfaction by different criteria than men do, placing greater emphasis on relationships with employers, staff, and clients. Interpersonal skills are integral to a positive and adaptive response to these societal and professional changes.There is limited information in the veterinary literature on veterinarian-client-patient communication, and what is available is predominantly based on expert opinion and anecdotal information, not p...

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Section: Patient Health-a Reviewmentioning

confidence: 99%

What can veterinarians learn from studies of physician-patient communication about veterinarian-client-patient communication?

Shaw¹,

Adams²,

Bonnett³

2004

javma

115

View full text Add to dashboard Cite

show abstract

“…The degree of compliance required to effect an adequate therapeutic outcome of antibacterial drug treatment is, however, difficult to assess. In the study by Bromzon (1978), 13 owners were questioned as to why there was more medicine left than should have been the case. The reason given by owners for being unable to follow the instructions was that because they were at work during the day, they were unable to treat the dog in the middle of the day.…”

Section: Dbscussionmentioning

confidence: 99%

Compliance with short‐term oral antibacterial drug treatment in dogs

Grave

Tanem

1999

J of Small Animal Practice

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Compliance with a 10-day course of oral antibacterial drugs in dogs being treated as outpatients at a veterinary clinic was assessed by use of pill count data obtained by telephone interview. The association between compliance and several possible determinants of compliance was investigated. Ninety-five animal owners were included in the study, with 44 per cent reporting 100 per cent compliance with the treatment regimen and as many as 88 per cent reporting a compliance level of 80 per cent or more. The compliance level was significantly higher (P < 0.002) when the animal owners felt that the veterinarians spent enough time on the consultation. Moreover, compliance was significantly higher (P < 0.05) for dogs being treated for gastrointestinal infections compared with those being treated for other diseases.

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“…Coincidental with the optimization of the PK/pharmacodynamic (PD) relationship through the maintenance of prolonged effective plasma concentrations are the patient benefits to be derived from requiring only intermittent administration by s.c. injection. Thus, not only would any potential problems and stress associated with repeated daily oral dosing be avoided, but it would also facilitate improved compliance with the prescribed dosing regimen by both owner and patient (Bomzon, 1978; Barter et al. , 1996; Grave & Tanem, 1999).…”

Section: Introductionmentioning

confidence: 99%

Pharmacokinetics of cefovecin in cats

Stegemann

Sherington

Coati

et al. 2006

Vet Pharm & Therapeutics

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The pharmacokinetics of the novel cephalosporin cefovecin were investigated in a series of in vivo, ex vivo and in vitro studies following administration to adult cats at 8 mg/kg bodyweight. Bioavailability and pharmacokinetic parameters were determined in a cross-over study after intravenous (i.v.) and subcutaneous (s.c.) injections. [14C]cefovecin was used to evaluate excretion for 21 days after s.c. administration. Protein binding was determined in vitro in feline plasma and ex vivo in transudate from cats surgically implanted with tissue chambers. After s.c. administration, cefovecin was characterized by rapid absorption with mean peak plasma concentrations of 141+/-12 microg/mL being achieved within 2 h of s.c. injection with full bioavailability (99%). The mean elimination half-life was 166+/-18 h. After i.v. administration, volume of distribution was 0.09+/-0.01 L/kg and mean plasma clearance was 0.35+/-0.04 mL/h/kg. Approximately 50% of the administered radiolabelled dose was eliminated over the 21-day postdose period via urinary excretion and up to approximately 25% in faeces. In vitro and ex vivo plasma protein binding ranged from 99.8% to 99.5% over the plasma concentration range 10-100 microg/mL. Ex vivo protein binding in transudate was as low as 90.7%. From 8 h postdose, concentrations of unbound (free) cefovecin in transudate were consistently higher than in plasma, with mean unbound cefovecin concentrations being maintained above 0.06 microg/mL (MIC90 of Pasteurella multocida) in transudate for at least 14 days postdose. The slow elimination and long-lasting free concentrations in extracellular fluid are desirable pharmacokinetic attributes for an antimicrobial with a 14-day dosing interval.

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Short–term antimicrobial therapy–a pilot compliance study using ampicillin in dogs

Cited by 17 publications

References 2 publications

What can veterinarians learn from studies of physician-patient communication about veterinarian-client-patient communication?

What can veterinarians learn from studies of physician-patient communication about veterinarian-client-patient communication?

Compliance with short‐term oral antibacterial drug treatment in dogs

Pharmacokinetics of cefovecin in cats

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