Short‐term antibiotic exposure affected the type and resistance of uropathogens similar to long‐term antibiotic prophylaxis in children hospitalised for urinary tract infections

Abstract

Aim: We investigated the impact of any antibiotic exposure on unusual and resistant pathogens in children with a urinary tract infection (UTI). Methods: This was a retrospective cohort study of 695 children (54% female

Update of the EAU/ESPU guidelines on urinary tract infections in children

“…Antimicrobial agents: There is a significant difference in prevalence patterns of antibiotic resistance of uropathogenic E. Coli in different countries, with increased high resistance patterns in countries outside The Organisation for Economic Cooperation and Development (OECD) [37]. Several risk factors and determinants for UTIs caused by ESBL and non-E Coli bacteria have been identified including history of infection, recent hospitalisation, short-term exposure to antibiotics, and prophylaxis [38,39]. The choice of antibiotics should be guided by good antibiotic stewardship.…”

2019 Update on Pediatric Medical Overuse

“…Antibiotic prophylaxis after urinary tract infections (UTIs) can prevent recurrences but has a high number needed to treat. Although studies have consistently demonstrated subsequent resistance to the antibiotic prescribed for prophylaxis, the consequences for multidrug resistance (defined in this study as resistance to antibiotics from ≥3 classes) has not been quantified. Urologists, nephrologists, general pediatricians, and hospitalists are the potential audiences for information on antibiotic prophylaxis after urinary tract infection.…”