Short Sleep Duration, Glucose Dysregulation and Hormonal Regulation of Appetite in Men and Women

St‐Onge, Marie‐Pierre; O’Keeffe, Majella; Roberts, Amy L.; RoyChoudhury, Arindam; Laferrère, Blandine

doi:10.5665/sleep.2198

Cited by 176 publications

(157 citation statements)

References 26 publications

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“…Experimental reductions in sleep duration support the claim that sleeping time could alter metabolic rates or affect the levels of appetite regulatory hormones such as leptin and ghrelin (30) . An association between insufficient sleep and increased energy intake has been demonstrated in some studies (29)(30)(31) . Sleep restriction was associated with an increase in energy consumption with no change in energy expenditure through PA or leptin and ghrelin concentrations (32) .…”

Section: Sleep In Weight Regulationmentioning

confidence: 77%

Long-term weight status in regainers after weight loss by lifestyle intervention: status and challenges

et al. 2014

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After having participated in a weight loss trial, most participants do not stabilise the obtained weight loss but return to their initial weight. The aim of this review is to describe the main determinants of continued low weight status after weight loss, and the effectiveness of physical activity (PA), energy restriction and macronutrient composition of the diet for low long-term weight regain. Studies with intervention periods of at least 3 months duration of weight reduction measures and a follow-up at least 2 years after the intervention period were considered as eligible for the review. Owing to limited data, the studies describing the role of PA in weight management were eligible with a follow-up of 1 year only. It appears that a diet with self-regulation of dietary intake seems to be given a prominent role in the strategy of successful long-term weight loss among the obese. This measure could be combined with behaviour therapy and PA and tailored to the individual situation. However, considering available evidence it is difficult to conclude regarding unambiguous measures and to recommend a specific dietary intervention. Nevertheless, interventions should be effective in promoting intrinsic motivation and self-efficacy. The harmonisation and standardisation of data collection in the follow-up period of long-term weight loss studies is a major challenge.

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Section: Sleep In Weight Regulationmentioning

confidence: 77%

Long-term weight status in regainers after weight loss by lifestyle intervention: status and challenges

et al. 2014

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“…The greater risk of obesity is possibly related to the effect of decreased sleep on hormones associated to appetite control and energy expenditure, specifically, the decrease of leptin plasma levels and the concomitant increase of grelin plasma levels in subjects with sleep restriction with the consequent increase of subjective appetite. 8,29,30 Furthermore, an association between sleep restriction and the different metabolic and endocrine alterations has been suggested, including insulin resistance without a compensatory increase in insulin secretion which results in impaired glucose tolerance and an increase in the risk of type 2 diabetes. 31,32 In short, evidence suggests that chronic sleep restriction likely contributes to the present epidemic of obesity and type 2 diabetes in the population.…”

Section: Discussionmentioning

confidence: 99%

Association between the amount of sleep and obesity in Chilean schoolchildren

2016

Arch Argent Pediat

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Introduction. Studies mainly performed in adults have shown an association between the amount of sleep and obesity. Objective. To determine if there is an association between nocturnal sleep deprivation during the week and the weekend, eating habits, physical activity and nutritional status among Chilean schoolchildren. Population, Material and Methods. Crosssectional study. An anthropometric assessment was done among 6-11 year-old students; the Pittsburgh Sleep Quality Index (PSQI) was used among parents to measure their children´s quality of sleep; they were asked about eating habits and physical activity. Results. One thousand eight hundred and ten schoolchildren of both sexes, attending public schools in Santiago, were assessed. Out of these schoolchildren, 49.9% slept fewer hours per night than recommended. An association in the crude model (crude OR 1.82; CI 95%: 1.29-2.56), in model 2 adjusted for cola drinks (OR 1.83; CI 95%: 1.30-2.59) and in model 3 adjusted for dinner, cola drink and caffeine beverage consumption and nocturia (OR 1.85; CI 95%: 1.30-2.62) was observed. It was also noticed that exercising was a protective factor against overweight and obesity; however, periodic limb movement during sleep was a risk factor. Conclusions. This study showed an association between fewer hours of sleep and an increase in the risk of overweight/obesity.

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“…In a study involving 14 days of CR, participants lost less fat mass when they spent 5.5 hr in bed per day than when they spent 8.5 hr in bed per day [11]. Additionally, an intervention involving a 4 day controlled diet combined with short sleep (4 hr in bed per day) induced less weight loss compared with habitual sleep (9 hr in bed per day) [19]. These studies suggest that sleep plays a role in the loss of weight and fat mass during CR.…”

Section: Introductionmentioning

confidence: 99%

Influence of sleep restriction on weight loss outcomes associated with caloric restriction

Wang

Sparks

Bowyer

et al. 2018

Sleep

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Study Objectives: To examine the effects of moderate sleep restriction (SR) on body weight, body composition, and metabolic variables in individuals undergoing caloric restriction (CR). Methods:Overweight or obese adults were randomized to an 8 week caloric restriction (CR) regimen alone (n = 15) or combined with sleep restriction (CR + SR) (n = 21). All participants were instructed to restrict daily calorie intake to 95 per cent of their measured resting metabolic rate. Participants in the CR + SR group were also instructed to reduce time in bed on five nights and to sleep ad libitum on the other two nights each week. Results:The CR + SR group reduced sleep by 57 ± 36 min per day during SR days and increased sleep by 59 ± 38 min per day during ad libitum sleep days, resulting in a sleep reduction of 169 ± 75 min per week. The CR and CR + SR groups lost similar amounts of weight, lean mass, and fat mass. However, the proportion of total mass lost as fat was significantly greater (p = 0.016) in the CR group. This proportion was greater than body fat percentage at baseline for the CR (p = 0.0035), but not the CR + SR group. Resting respiratory quotient was reduced (p = 0.033) only in CR, and fasting leptin concentration was reduced only in CR + SR (p = 0.029).Conclusions: Approximately 1 hr of SR on five nights a week led to less proportion of fat mass loss in individuals undergoing hypocaloric weight loss, despite similar weight loss. SR may adversely affect changes in body composition and "catch-up" sleep may not completely reverse it. Clinical trial registration: ClinicalTrials.gov (NCT02413866)Key words: sleep restriction; weight loss; body composition; chronic; caloric restriction Statement of SignificancePrevious studies suggest that sleep restriction during caloric restriction adversely affects weight-loss outcomes. This study extends previous findings by examining the effects of a much longer duration of intervention (8 weeks) using a randomized controlled trial (caloric restriction alone or combined with sleep restriction). Furthermore, the sleep restriction was moderate, approximated 60 min shorter on the 5 days of restricted sleep each week. Ad libitum sleep was allowed on the other 2 days each week so that the sleep pattern mimicked real life. We found that sleep restriction resulted in less loss of fat but greater loss of lean mass among the total mass lost, despite similar weight loss between the two groups. Other metabolic changes were also observed.

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Short Sleep Duration, Glucose Dysregulation and Hormonal Regulation of Appetite in Men and Women

Abstract: Trial registration on http://www.clinicaltrials.gov. #NCT00935402.

Cited by 176 publications

References 26 publications

Long-term weight status in regainers after weight loss by lifestyle intervention: status and challenges

Long-term weight status in regainers after weight loss by lifestyle intervention: status and challenges

Association between the amount of sleep and obesity in Chilean schoolchildren

Influence of sleep restriction on weight loss outcomes associated with caloric restriction

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