Abstract::
A practical and concise total synthesis of tricyclic ketone 7 (CDE ring), a valuable intermediate for the synthesis of
racemic camptothecin and analogs, was described (8 chemical steps and 29% overall yield). The synthesis starts with
two inexpensive, readily available materials and is operationally simple to perform. It is worth mentioning that the
reported protecting group-free synthesis, with advantages of a short route, would be helpful for the future development
of industry scale syntheses of camptothec… Show more
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