Short daily hemodialysis rapidly improves nutritional status in hemodialysis patients

Galland, Roula; Traeger, J; Arkouche, Walid; Cleaud, Christine; Delawari, Ehsan; Fouque, Denis

doi:10.1046/j.1523-1755.2001.00959.x

Cited by 137 publications

(77 citation statements)

References 20 publications

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“…Several uncontrolled studies reported significant improvements in health-related quality of life when subjects were treated with more frequent in-center or home hemodialysis (23,45,50). Better control of uremia may have improved perceptions of wellbeing (23,28,51). In the Daily Trial, frequent hemodialysis increased extracellular fluid removal and as a result, may have improved selfperceived physical health and functioning through enhanced mobility and less fatigue, although no objective improvement in gait speed was observed (23).…”

Section: Discussionmentioning

confidence: 99%

“…Although increasing the per-session dose of dialysis (Kt/V urea ) led to better preservation of self-reported physical health and functioning among patients receiving hemodialysis three times per week (5), relatively little is known about whether and to what extent the frequency of dialysis influences overall physical health (21,22). Frequent compared with conventional hemodialysis might improve physical functioning through better control of uremia, improvement in exercise capacity, preservation of nutritional status and muscle mass, correction of acid-base imbalances, and reduction of interdialytic weight gain and hypervolemia (23)(24)(25)(26)(27)(28).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effects of Six versus Three Times per Week Hemodialysis on Physical Performance, Health, and Functioning

Hall

Larive

Painter

et al. 2012

Clinical Journal of the American Society of Nephrology

104

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SummaryBackground and objectives Relatively little is known about the effects of hemodialysis frequency on the disability of patients with ESRD.Design, setting, participants, & measurements This study examined changes in physical performance and selfreported physical health and functioning among subjects randomized to frequent (six times per week) compared with conventional (three times per week) hemodialysis in both the Frequent Hemodialysis Network daily (n=245) and nocturnal (n=87) trials. The main outcome measures were adjusted change in scores over 12 months on the short physical performance battery (SPPB), RAND 36-item health survey physical health composite (PHC), and physical functioning subscale (PF) based on the intention to treat principle.Results Overall scores for SPPB, PHC, and PF were poor relative to population norms and in line with other studies in ESRD. In the Daily Trial, subjects randomized to frequent compared with conventional in-center hemodialysis experienced no significant change in SPPB (adjusted mean change of 20.2060.19 versus 20.4160.21, P=0.45) but experienced significant improvement in PHC (3.460.8 versus 0.460.8, P=0.009) and a relatively large change in PF that did not reach statistical significance. In the Nocturnal Trial, there were no significant differences among subjects randomized to frequent compared with conventional hemodialysis in SPPB ( Conclusions Frequent in-center hemodialysis compared with conventional in-center hemodialysis improved self-reported physical health and functioning but had no significant effect on objective physical performance. There were no significant effects of frequent nocturnal hemodialysis on the same physical metrics.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effects of Six versus Three Times per Week Hemodialysis on Physical Performance, Health, and Functioning

Hall

Larive

Painter

et al. 2012

Clinical Journal of the American Society of Nephrology

104

View full text Add to dashboard Cite

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“…Beneficial effects of frequent dialysis (HD or HDF) have been reported for several cardiovascular risk factors, renal anemia, hyperphosphatemia control and improvement of nutritional status [12,22]. …”

Section: Discussionmentioning

confidence: 99%

Treatment Frequency and Efficiency in Hemodiafiltration

et al. 2013

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Background: One of the main objectives of dialysis is uremic retention product elimination. Efficiency of dialysis modalities varies both regarding the range of solutes removed and the extent of such removal. We analyzed plasma (or blood) concentrations of marker solutes in intermittent treatment schedules using hemodiafiltration (HDF). Methods: Elimination and rebound of uremic solutes were measured in 10 patients (77 ± 12 kg, 66.5 ± 9.2 years) treated with postdilution HDF in one 4-hour treatment and in two 2-hour treatments on consecutive days (Polyflux 2.1 m², QB 451 ± 53 ml/min, QD 598 ± 13 ml/min). Blood urea, creatinine, phosphate, β₂-microglobulin, complement factor D and advanced glycation end products were analyzed before, during and after HDF for 24-48 h. Results: Applying two 2-hour HDF treatments on consecutive days resulted in significantly lower plasma (or blood) levels of urea, creatinine, phosphate, β₂-microglobulin, and advanced glycation end products after 48 h than using one 4-hour session. Conclusions: Increased treatment frequency could further optimize blood purification in HDF therapy.

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“…The better ultrafiltration rate has been associated with better control of blood pressure [33,36,37], where the majority of dialysis patients discontinued antihypertensive medications after 6-12 months of daily/nocturnal dialysis [30,115]. Increasing dialysis frequency, and in particular nocturnal HD, has also been linked to significant improvement in renal anemia [31,116] and reduction in erythropoietin dosage and iron supplements [115], significant reduction in left ventricular mass index [33,36,117], improvement in mineral metabolism and significant reduction in phosphorus binders [33,36,37,114], improvement in nutritional status [30,118], enhanced quality of life [33,36,119] and increased cumulative survival rate [34]. Moreover, patients on nocturnal HD have a similar survival rate as that in deceased kidney transplant recipients [120].…”

Section: Frequent Hemodialysismentioning

confidence: 99%

Advances in Hemodialysis Techniques

Karkar¹

2013

Hemodialysis

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Short daily hemodialysis rapidly improves nutritional status in hemodialysis patients

Abstract: Daily hemodialysis appears to be a suitable method to improve nutritional status in maintenance dialysis patients.

Cited by 137 publications

References 20 publications

Effects of Six versus Three Times per Week Hemodialysis on Physical Performance, Health, and Functioning

Effects of Six versus Three Times per Week Hemodialysis on Physical Performance, Health, and Functioning

Treatment Frequency and Efficiency in Hemodiafiltration

Advances in Hemodialysis Techniques

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