SHORT CU MMUNICA TION: OCCURRENCE OF THE IMMUNOGLOBULIN HAPLOTYPES Gm^1,17;23;21 AND Gm^1,2,17;23;21 IN A SAMPLE OF AUSTRALIAN CAUCASIANS

Abstract

SUMMARY Phenotypes positive for G2m(23) but negative for Glm(3) and G3m(5,10,11,13,14) are generally very infrequent in Caucasian populations. We recently Gm typed 372 Australian blood donors, predominantly of European descent, and found two Gm(1;23) and five Gm(1,2;23) individuals among them. This finding suggests that the haplotypes Gm1,17:23;21 and Gm1,2,17,23,21 may occur, in some European populations, with a frequency considerably higher than has been generally assumed.