2018
DOI: 10.1007/s00134-018-5088-x
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Short-course antibiotic therapy for critically ill patients treated for postoperative intra-abdominal infection: the DURAPOP randomised clinical trial

Abstract: NCT01311765.

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Cited by 137 publications
(105 citation statements)
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References 31 publications
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“…Maseda et al 32) conducted a study to evaluate the efficacy of a procalcitonin (PCT)-guided antibiotic therapy in patients who are critically ill with secondary peritonitis. The severity of their patients' illnesses, with a mean SAPS II score of 43.4, was comparable with that reported by Montravers et al 31) . The duration of treatment was significantly shorter in the PCT-guided group than in the non-PCT-guided group (5.1 ± 2.1 vs. 10.2 ± 3.7 days, respectively) without affecting the outcome.…”
Section: ) High Severity Scoresupporting
confidence: 87%
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“…Maseda et al 32) conducted a study to evaluate the efficacy of a procalcitonin (PCT)-guided antibiotic therapy in patients who are critically ill with secondary peritonitis. The severity of their patients' illnesses, with a mean SAPS II score of 43.4, was comparable with that reported by Montravers et al 31) . The duration of treatment was significantly shorter in the PCT-guided group than in the non-PCT-guided group (5.1 ± 2.1 vs. 10.2 ± 3.7 days, respectively) without affecting the outcome.…”
Section: ) High Severity Scoresupporting
confidence: 87%
“…The duration of treatment was significantly shorter in the PCT-guided group than in the non-PCT-guided group (5.1 ± 2.1 vs. 10.2 ± 3.7 days, respectively) without affecting the outcome. This study suggests that the duration of antibiotic therapy may be shorter than the 8-day regimen proposed by Montravers et al 31) after adequate source control surgery in patients who are critically ill.…”
Section: ) High Severity Scorementioning
confidence: 59%
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“…Verschiedene Definitionen wurden international publi- Procalcitonin ist ein möglicher Baustein bei der zu entscheidenden Frage, ob eine Antibiotikatherapie beendet werden kann. Die Ergebnisse bei IAI sind aber unterschiedlich, sodass der wahre Wert von Procalcitonin zur Therapiesteuerung bei abdomineller Sepsis derzeit nicht bestimmt werden kann [26,37].…”
Section: Operationale Definitionenunclassified
“…The prevalence of nosocomial infections caused by a Gramnegative opportunistic pathogen, Stenotrophomonas maltophilia, has remarkably increased in recent years [1][2][3][4][5][6][7]. S. maltophilia is ubiquitously widespread in the water, soil, plants, animals, and foods [8,9].…”
Section: Introductionmentioning
confidence: 99%