“…Thirty-nine variants, among them 25 missenses, four nonsenses, three splice-sites, four frameshifts, and three in the promoter region were published from June 2013 to February 2017 in a total of 109 out of 829 SRNS patients in many countries: China (Wang et al, 2017) [28]; India (Jaffer et al, 2014; Dhandapani et al 2017; Ramanathan et al 2017) [29–31]; Italy (Benetti et al, 2013) [32]; Iran (Basiratnia et al, 2013) [33]; United Kingdom (Jain et al, 2014) [34]; United States of America (Laurin et al, 2014; Phelan et al, 2015) [35, 36]; Poland (Kuleta et al, 2014) [37]; Finland (Suvanto et al, 2016) [38]; Saudi Arabi (Kari et al, 2013) [39]; Japan (Ogino et al, 2015) [40]; Mexico (Carrasco-Miranda et al, 2013) [41]; Chile (Azocar et al, 2016) [42]; and Brazil (Guaragna et al, 2015) [43]. Ten out of those 39 mutations were unique and had not been annotated in public HGMD (http://www.hgmd.cf.ac.uk/ac/index.php) or in GnomeAD Browser (http://gnomad.broadinstitute.org) or in the Leiden Open Variation Database (https://www.lovd.nl/NPHS2): six were missenses, three were located in splice-site regions, and two were frameshifts (Table 1).…”