SHORT COMMUNICATION: Detection of complement regulatory proteins on soft contact lenses

Ds, Bardenstein; Sauer, SJ; Szczotka, Loretta B.; Me, Medof

doi:10.1076/ceyr.16.12.1270.5028

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Cited by 7 publications

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“…Our data provide additional evidence that in the eye a regulatory system exists to protect the eye from destruction by complement activation, as has been proposed by others [2,4,20] and was shown in the case of AMD [16].…”

Section: Discussionsupporting

confidence: 65%

Enhanced expression of the complement factor H mRNA in proliferating human RPE cells

Kociok

Joussen

2010

Graefes Arch Clin Exp Ophthalmol

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The identification of the differential expression of the regulatory factors H and I of the complement system in cultured RPE cells by a technique without any prerequisites demonstrates and confirms the importance of these factors in RPE cells. In addition to its known role in age-related macular degeneration, the presence of these complement factors in epiretinal membranes may also indicate a role of the complement system in proliferative retinopathy.

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Section: Discussionsupporting

confidence: 65%