Short Bowel Syndrome

Navarro, Fernando A.; Gleason, Wallace A.; Rhoads, J. Marc; Quirós-Tejeira, Rubén E.

doi:10.1542/neo.10-7-e330

Cited by 5 publications

(2 citation statements)

References 57 publications

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“…Normally, the length of the small bowel in a term infant is about 250 cm. [ 3 ] There is rapid growth and elongation of the small bowel until the crown-heel length is 60 cm, after which the length of the small bowel remains relatively constant until a body length of 140 cm. [ 4 ] The signs and symptoms of SBS manifest in term infants when the length of the small bowel is less than 75 cm.…”

Section: Discussionmentioning

confidence: 99%

Case report: Congenital short bowel syndrome

Lalitha¹,

Reddy²

2010

Indian Journal of Radiology and Imaging

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Congenital short bowel syndrome (SBS) is a relatively rare condition as compared to acquired SBS. It is associated with significant mortality and morbidity. Infants usually present with failure to thrive, recurrent vomiting, and diarrhea. It is important to suspect and diagnose this condition promptly, as early initiation of parenteral nutrition or surgery, if necessary, may result in a favorable outcome. We discuss a case of an infant aged 26 days, who presented with failure to thrive, recurrent vomiting, and weight loss. A contrast study of the gastrointestinal tract revealed a short small bowel, with malrotation. The infant was started on parenteral nutrition, but succumbed shortly thereafter to severe disseminated sepsis.

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Section: Discussionmentioning

confidence: 99%

Case report: Congenital short bowel syndrome

Lalitha¹,

Reddy²

2010

Indian Journal of Radiology and Imaging

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“…Surgical SBS secondary to neonatal necrotizing enterocolitis occurs in 1.1% of very-low birth weight infants, with a mortality rate of 20%. 2,3 Ultra SBS (Class I SBS) refers to a subset of severely affected patients with less than 15 cm of residual total bowel.…”

Section: Introductionmentioning

confidence: 99%

Ethics of emerging technologies and their transition to accepted practice: intestinal transplant for short bowel syndrome

Cummings,

Mercurio

2012

J Perinatol

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Parental counseling becomes complex when considering the use of emerging technologies, especially if it is unclear whether the level of evidence is sufficient to transform the proposed therapy into accepted practice. This paper addresses ethical issues underlying medical decisionmaking and counseling in the setting of emerging treatments, when longterm outcomes are still in the process of being fully validated. We argue that the ethical transition of emerging technologies, ideally from ethically impermissible to permissible, to obligatory, depends primarily on two factors: outcome data (or prognosis) and treatment feasibility. To illustrate these points, we will use intestinal transplant for short bowel syndrome (SBS) as a specific example. After reviewing the data, this paper will identify the ethical justifications for both comfort care only and intestinal transplant in patients with ultra SBS, and argue that both are ethically permissible, but neither is obligatory. The approach outlined will not only be valuable as ultra SBS outcomes data continue to change, but will also be applicable to other novel therapies as they emerge in perinatal medicine.

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Etiology and Epidemiology of Intestinal Failure

Cole¹,

Ziegler²

2011

Clinical Management of Intestinal Failure

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Short Bowel Syndrome

Cited by 5 publications

References 57 publications

Case report: Congenital short bowel syndrome

Case report: Congenital short bowel syndrome

Ethics of emerging technologies and their transition to accepted practice: intestinal transplant for short bowel syndrome

Etiology and Epidemiology of Intestinal Failure

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