Short and Midterm Outcomes in Patients With Acute Myocardial Infarction: Results of the Nationwide TURKMI Registry

Kılıçkap, Mustafa; Erol, Mustafa Kemal; Kayıkçıoğlu, Meral; Kocayiğit, İbrahim; Gitmez, Mesut; Can, Veysi; Beşli, Feyzullah; Şabanoğlu, Cengiz; Ünğan, İsmail; Genç, Ahmet; Karatas, Mesut; Dursun, İhsan; Öztekin, Gülsüm Meral Yılmaz; Candemir, Aytaç; Çelik, Yunus; Yanık, Ahmet; Halac, Aylin Hatice Yamaç; Aktürk, İbrahim Faruk; Sünbül, Murat; Sarıkaya, Remzi; Arı, Hasan; Yalçın, Ahmet Arif; Güneş, Hakan

doi:10.1177/0003319720975302

Cited by 8 publications

(5 citation statements)

References 21 publications

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“…As previously described [30], we found that STEMI was more lethal than NSTEMI. In this way, the probability of dying in COPD men was 2.33 times higher among those with STEMI than among those with NSTEMI.…”

Section: Discussionsupporting

confidence: 83%

Sex Differences in the Effects of COPD on Incidence and Outcomes of Patients Hospitalized with ST and Non-ST Elevation Myocardial Infarction: A Population-Based Matched-Pair Analysis in Spain (2016–2018)

de-Miguel-Díez

Jiménez-García

Hernández‐Barrera

et al. 2021

JCM

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We aimed to compare the incidence, clinical characteristics, and outcomes of patients admitted with myocardial infarction (MI), whether ST elevation MI (STEMI) or non-ST elevation MI (NSTEMI), according to the presence of chronic obstructive pulmonary disease (COPD), and to identify variables associated with in-hospital mortality (IHM). We selected all patients with MI (aged ≥40 years) included in the Spanish National Hospital Discharge Database (2016–2018). We matched each patient suffering COPD with a non-COPD patient with identical age, sex, type of MI, and year of hospitalization. We identified 109,759 men and 44,589 women with MI. The MI incidence was higher in COPD patients (incident rate ratio (IRR) 1.32; 95% confidence interval (CI) 1.29–1.35). Men with COPD had higher incidence of STEMI and NSTEMI than women with COPD. After matching, COPD men had a higher IHM than non-COPD men, but no differences were found among women. The probability of dying was higher among COPD men with STEMI in comparison with NSTEMI (odds ratio (OR) 2.33; 95% CI 1.96–2.77), with this risk being higher among COPD women (OR 2.63; 95% CI 1.75–3.95). Suffering COPD increased the IHM after an MI in men (OR 1.14; 95% CI 1.03–1.27), but no differences were found in women. COPD women had a higher IHM than men (OR 1.19; 95% CI 1.01–1.39). We conclude that MI incidence was higher in COPD patients. IHM was higher in COPD men than in those without COPD, but no differences were found among women. Among COPD patients, STEMI was more lethal than NSTEMI. Suffering COPD increased the IHM after MI among men. Women with COPD had a significantly higher probability of dying in the hospital than COPD men.

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Section: Discussionsupporting

confidence: 83%

Sex Differences in the Effects of COPD on Incidence and Outcomes of Patients Hospitalized with ST and Non-ST Elevation Myocardial Infarction: A Population-Based Matched-Pair Analysis in Spain (2016–2018)

de-Miguel-Díez

Jiménez-García

Hernández‐Barrera

et al. 2021

JCM

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“…The TURKMI registry demonstrated that PCI was performed in Turkey with a low risk of complication in acute MI. This study also showed that the risk of in-hospital mortality decreased by 50% during 20 years probably due to an increased number of PCI and high level of guideline implementation [12].…”

Section: Discussionsupporting

confidence: 51%

Opinions of cardiologists on class II recommendations in current European Society of Cardiology 2018-2020 guidelines: YELLOW BOX

KIŞ

Güzel

EKİCİ

et al. 2022

The European Research Journal

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Objectives:We planned our survey study to evaluate the opinion of cardiologists about the class II recommendations on levels of evidence in the current European Society of Cardiology Guidelines (ESC). Our aim is to determine which diagnosis or treatment option most prefer by cardiologist when guidelines do not make clear recommendations. Methods: The survey was conducted on September 2020 with the participation of cardiologists (n = 102). Our survey covers ESC's guidelines published in 2018-2020 on diagnosis and treatment strategies in coronary artery disease, diabetes, heart valve disease, arrhythmia, dyslipidemia and heart failure. Our survey consisting of 40 questions was shared with the cardiologists via e-mail. Results: Participants answered all of the survey questions. The majority of the participants (79.41%) did not consider the addition of a second long-term antithrombotic medication in addition to aspirin for secondary prevention in diabetes mellitus (DM) and coronary artery disease (CAD) patients who are not at high risk of bleeding. The lowest low density lipoprotein (LDL) value achieved by the participant physicians with treatment in their practices was < 40 mg/dl in 32 (31.37%) participants. One of the striking results of the survey was that 51.96% of the participants stated that it was not possible to measure the lipoprotein a (Lp(a)) level in the center where they were carrying out their practices, and 34.31% did not consider the Lp(a) level in the treatment of dyslipidemia in terms of directing the treatment. As for patients with asymptomatic Wolff-Parkinson-White (WPW) syndrome, 58.82% of the participants considered catheter ablation therapy. Conclusions: Although there were different opinions on some recommendations, the participants were mostly in agreement. We think that these survey results, which were mostly based on expert opinions, may contribute to the guidelines to be published in the future with the increase of survey studies on these issues.

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“…Greater lesion size and higher plaque density contribute to higher cardiovascular mortality in women than men with extensive calcified disease. 130 Irrespective of the pathophysiology, women with acute coronary syndrome tend to have poorer outcomes than men, 132 reflecting increased comorbidities, and delays and underuse of guideline-recommended treatment. 133 , 134 …”

Section: Does Atherosclerotic Cardiovascular Disease Presentation Dif...mentioning

confidence: 99%

Women, lipids, and atherosclerotic cardiovascular disease: a call to action from the European Atherosclerosis Society

Roeters van Lennep,

Tokgözoğlu,

Badimon

et al. 2023

European Heart Journal

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Cardiovascular disease is the leading cause of death in women and men globally, with most due to atherosclerotic cardiovascular disease (ASCVD). Despite progress during the last 30 years, ASCVD mortality is now increasing, with the fastest relative increase in middle-aged women. Missed or delayed diagnosis and undertreatment do not fully explain this burden of disease. Sex-specific factors, such as hypertensive disorders of pregnancy, premature menopause (especially primary ovarian insufficiency), and polycystic ovary syndrome are also relevant, with good evidence that these are associated with greater cardiovascular risk. This position statement from the European Atherosclerosis Society focuses on these factors, as well as sex-specific effects on lipids, including lipoprotein(a), over the life course in women which impact ASCVD risk. Women are also disproportionately impacted (in relative terms) by diabetes, chronic kidney disease, and auto-immune inflammatory disease. All these effects are compounded by sociocultural components related to gender. This panel stresses the need to identify and treat modifiable cardiovascular risk factors earlier in women, especially for those at risk due to sex-specific conditions, to reduce the unacceptably high burden of ASCVD in women.

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Short and Midterm Outcomes in Patients With Acute Myocardial Infarction: Results of the Nationwide TURKMI Registry

Cited by 8 publications

References 21 publications

Sex Differences in the Effects of COPD on Incidence and Outcomes of Patients Hospitalized with ST and Non-ST Elevation Myocardial Infarction: A Population-Based Matched-Pair Analysis in Spain (2016–2018)

Sex Differences in the Effects of COPD on Incidence and Outcomes of Patients Hospitalized with ST and Non-ST Elevation Myocardial Infarction: A Population-Based Matched-Pair Analysis in Spain (2016–2018)

Opinions of cardiologists on class II recommendations in current European Society of Cardiology 2018-2020 guidelines: YELLOW BOX

Women, lipids, and atherosclerotic cardiovascular disease: a call to action from the European Atherosclerosis Society

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