Short- and medium-term follow-up of transcatheter closure of perimembranous ventricular septal defects

Abstract

Background Transcatheter closure of perimembranous ventricular septal defects is one of the greatest challenges in interventional cardiology. Short- and midium-term follow-up data for large samples are limited. This report presents our experience with transcatheter closure of perimembranous ventricular septal defects using an occluder. Methods Two hundred fifty-three patients included in the database of the Second Affiliated Hospital and Yuying Children’s Hospital from January 2011– December 2015 with transcatheter closure of perimembranous ventricular septal defects and discharged from follow-up. All patients were invited for clinical and transthoracic echocardiography, electrocardiogram, and thoracic radiography check-up. Results Device implantation was successful in 252 of 253 patients (99.6%). The median age was 42 months (range 27–216 months). The median follow-up duration was 36 months (range 6–60 months). The mean defect diameter was 3.5 ± 1.4 mm and the mean size of the ventricular septal defect rim below the aortic valve was 3.7 ± 1.8 mm. The mean diameter of the devices used was 4 mm. Thirty-seven patients developed arrhythmia after the procedure and recovered within 24 months; four patients had hemolysis and four had moderate tricuspid valve regurgitation. No other serious adverse event occurred during the follow-up period. Conclusion Transcatheter closure of perimembranous ventricular septal defects using an occluder is safe and effective in most patients.

Left Anterior Fascicular Block After Transcatheter Closure of Ventricular Septal Defect in Children

“…The incidence of postprocedural LAFB ranges from 3.6 to 5.5% as reported by other centers (13)(14)(15). Our results indicate that postprocedural LAFB has an incidence of 2.2% (30/1,371) among all patients and 11.8% (30/255) among all postprocedural arrhythmias, and it is not that low, especially among postprocedural BBB (23.3%, 30/129).…”

Transcatheter Device Closure of Perimembranous and Intracristal Ventricular Septal Defects in Children: Medium‐ and Long‐Term Results

“…cAVB has been considered to be the most serious complication, 2 , 11 with rate of incidence gradually decreasing to 1% in recent years. 12 , 13 , 14 CLBBB draws more attention because definite proof from clinical and experimental studies has identified that CLBBB might cause abnormal LV contraction and deteriorate LV function, which could induce progressive LV remodeling and heart failure. 15 Special attention was paid to the possibility of recurrence and late onset of cAVB and CLBBB.…”

Comparison of Health-Related Quality of Life in Adults Undergoing Transthoracic and Transcatheter Device Closure for Ventricular Septal Defects

“…However, there has been no cross-sectional comparison between the two treatments, so research on the different effects of these two treatments on the postoperative HRQoL of adult patients is still needed. [18][19][20][21] In this study, we found that there was no significant difference in SF-36 scores between groups A and B except for the two dimensions of vitality and mental health. The reason might be that the patients subjectively felt that the transcatheter procedure had less impact on the body than the transthoracic procedure and thus had more positive feedback in the psychological domain.…”