Short and long-term results of sternectomy for sternal tumours

Bongiolatti, Stefano; Voltolini, Luca; Borgianni, Sara; Borrelli, Roberto; Innocenti, Marco; Menichini, Giulio; Politi, Lucia; Tancredi, Giorgia; Viggiano, Domenico; Gonfiotti, Alessandro

doi:10.21037/jtd.2017.10.94

Cited by 19 publications

(27 citation statements)

References 24 publications

(61 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Partial or total sternectomy for solitary metastatic sternal deposits is well established with relatively low morbidity, mortality and improvement in quality of life and long-term survival [ 7 ]. Interestingly, the aspect of chest wall or sternal pain is one aspect that considerably improves following sternal metastasectomy.…”

Section: Discussionmentioning

confidence: 99%

Excision of metastatic breast cancer from sternum and reconstruction in two patients with solitary metastatic spread

Mohamed

Mazhar

Osman

et al. 2020

Journal of Surgical Case Reports

View full text Add to dashboard Cite

Metastatic breast carcinoma is a relatively common clinical entity. However, the prognosis of oligometastatic and polygometastatic disease differs considerably pertaining to five-year survival. Metastatic breast carcinoma to the sternum has been described as early as 1988. We describe two cases in our institution who presented with solitary sternal metastases with a previous history of treated breast cancer. In both cases, there had been a history of previous left breast cancer treated aggressively with surgical resection and adjuvant oncological therapy and maintenance hormonal therapy. Partial sternectomy or total sternectomy for solitary metastatic sternal deposits is well established with relatively low morbidity and mortality and improvement in quality of life and possible improvement in long-term survival. Furthermore, reconstructive options are inherently dependent on extent of resection performed. These techniques can incorporate the use of sternal plates in order to approximate defects and reinforce the sternum in the setting of partial sternectomy.

show abstract

Section: Discussionmentioning

confidence: 99%

Excision of metastatic breast cancer from sternum and reconstruction in two patients with solitary metastatic spread

Mohamed

Mazhar

Osman

et al. 2020

Journal of Surgical Case Reports

View full text Add to dashboard Cite

show abstract

“…Overall 5-year survival rate in the chondrosarcoma group was 80%. Bongiolatti et al (13) reported 36 sternal resection and reconstruction, 50% of which for chondrosarcoma. Reconstruction was made using the STRATOS system combined with a muscle flap and/or PTFE (30.5%), ePTFE patch (16.7%), and bilateral pectoralis major myocutaneous advancement flaps (52.7%).…”

Section: Reconstructive Techniquesmentioning

confidence: 99%

Complex anterior chest wall reconstruction after extensive oncologic resections: a narrative review

Gritsiuta¹,

Bracken²,

Abbas³

et al. 2021

Shanghai Chest

View full text Add to dashboard Cite

Objective: This report serves to showcase four cases of rare, malignant primary neoplasms of the anterior chest wall [chondrosarcoma and basal cell carcinoma (BCC)] that thoracic surgeons may encounter, and different approaches to complex reconstruction that may be necessary following resection.Background: Approximately 60% of the anterior chest wall neoplasms are malignant. The most common types of primary sternal tumors are chondrosarcoma and osteosarcoma. While guidelines for resection of these tumors have been previously described in the literature, guidelines regarding reconstructive techniques of the subsequent large defects are infrequently demonstrated. Methods:The medical records of four adult patients with primary chest wall tumors who underwent resection of the sternum from October 2016 to March 2021 were retrospectively reviewed. Radical resection with tumor-free surgical margins offers the best chance for survival, but results in a wide full-thickness defect. Hence, closure of the anterior chest wall defect with skeletal reconstruction is an essential step of the procedure and allows us to highlight surgical techniques and materials that have been used over recent years.Methods described herein include skeletal reconstruction with various hardware or allograft, as well as defect coverage using regional flaps, free tissue transfer, and mesh.Conclusions: Primary chest wall tumors of the sternum are an extremely rare diagnosis with a high malignancy rate. Full-thickness radical en-bloc resection is the most effective treatment option. Subsequent reconstruction of a wide chest wall defect is the most challenging aspect, though crucial in the preservation of the rigidity of the chest wall and protection of underlying structures. Different techniques and materials have been described without clear guidelines in treatment approaches; this paper serves to delineate and describe techniques that achieved successful outcomes.

show abstract

“…Holden first described partial sternectomy for a primary sarcoma in 1878 [3] and the first complete sternectomy was performed by Brodin and Linden in 1959 [4]. Sternal resection with immediate reconstruction of the anterior chest wall defect was recommended for both primary and secondary sternal tumors as curative treatment [5].…”

Section: Introductionmentioning

confidence: 99%

Oncological Outcome of Surgically Resected Sternal Tumors, 16 Years’ Experience

Abdelrahman

Ismail

Ghaly

et al. 2022

Open Access Maced J Med Sci

View full text Add to dashboard Cite

BACKGROUND: Tumors of the sternum are rare and can develop from primary bone pathology or through metastatic spread. Sternal resection with immediate reconstruction of the anterior chest wall defect was recommended for both primary and secondary sternal tumors as curative treatment. AIM: The purpose of our study was to examine the perioperative outcomes, recurrence rate, and OS in patients undergoing partial, subtotal, and total sternectomy. METHODS: We retrospectively reviewed our experience with sternal resections in 29 patients during a 16-year period. The purpose of our study was to examine the perioperative outcomes, recurrence rate, and overall survival (OS) in patients undergoing partial, subtotal, and total sternectomy. RESULTS: We found that 5-year OS was 26.0%, Univariate analysis of predictors of survival revealed that, there was a trend toward prolonged 5-year survival at R0 resection (35.5% vs. 0%, p = 0.058). Post resection defect size associated with prolonged 5-year OS (42.1% vs. 0%, p < 0.001). The absence of post-operative complications associated with prolonged 5-year OS (40.4% vs. 0%, p = 0.012), with special attention to absence of post-operative flail chest which was associated with prolonged 5-year OS (36.2% vs. 0%, p < 0.001). On multivariable analysis, R0 resection (HR, 3.692 [95% CI, 1.190–11.456], p = 0.024) and absence of post-operative flail chest (HR, 52.204 [95% CI, 5.908–461.289], p < 0.001) were associated with improved OS. CONCLUSIONS: We have shown that sternal resection of benign and primary malignant tumors can yield long-term survival. The completeness of resection and absence of postoperative flail chest are the strongest predictors of survival.

show abstract

Short and long-term results of sternectomy for sternal tumours

Cited by 19 publications

References 24 publications

Excision of metastatic breast cancer from sternum and reconstruction in two patients with solitary metastatic spread

Excision of metastatic breast cancer from sternum and reconstruction in two patients with solitary metastatic spread

Complex anterior chest wall reconstruction after extensive oncologic resections: a narrative review

Oncological Outcome of Surgically Resected Sternal Tumors, 16 Years’ Experience

Contact Info

Product

Resources

About