Shock wave-enhanced neovascularization at the tendon-bone junction: An experiment in dogs

Wang, Ching‐Jen; Huang, Hsuan-Ying; Pai, Chun-Hwan

doi:10.1016/s1067-2516(02)80005-9

Cited by 254 publications

(200 citation statements)

References 13 publications

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“…[17][18][19] Others report that the ESWT would involve a stimulation of a neovascularization. 17,20,21 Another probable explanation given by Zhao et al 10 is the alteration of the afferent pain mechanisms. Those authors used ESWT on individuals with knee osteoarthritis and also found a reduction in pain intensity as measured by VAS after treatment.…”

Section: Discussionmentioning

confidence: 99%

Influence of shockwave therapy on pain in women with knee osteoarthritis

Imamura¹,

Alfieri²,

Plapler³

et al. 2015

Acta Fisiátrica

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Osteoarthritis is the most common articular disease that causes pain to its sufferers. Shockwave therapy is among the many treatments that can be used. Objective: The objective of this study was to observe the influence of shockwave therapy on the intensity of pain in elderly women with knee OA. Method: In this study, 40 elderly females (69.57 ± 6.42 years) were submitted to weekly shockwave therapy with 2000 impulses at 2.5 to 4.0 bar, at a frequency of 8Hz, at the location most painful to touch in the knee, the medial articular interline, for three consecutive weeks. The effect of its application on the pain was evaluated by the visual analogue scale before and after the treatment. Results: There was a significant reduction (p < 0.0001) of pain intensity in the volunteers, going from 7.86 ± 1.07 cm to 5.32 ± 2.26 cm. Conclusion: The application of shockwave therapy has been shown to reduce pain in elderly females with osteoarthritis. Keywords

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Section: Discussionmentioning

confidence: 99%

Influence of shockwave therapy on pain in women with knee osteoarthritis

Imamura¹,

Alfieri²,

Plapler³

et al. 2015

Acta Fisiátrica

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“…20 Most of the observed changes with the use of ESWT in man have been observed on examination of non-musculo- skeletal tissues, particularly the kidney, and most of the information available on the effects on musculoskeletal tissues is based on animal studies. [21][22][23] Studies of the effect of shock waves on tendo Achillis of the rabbit have indicated a dose-dependent effect, a transient inflammatory reaction and swelling of the tendon with 1000 impulses of higher (0.28 mJ/mm 2 ) but not lower (0.08 mJ/mm 2 ) doses. 24 Fibrinoid necrosis, paratenon fibrosis and marked inflammatory changes were seen with even higher doses (0.60 mJ/ mm 2 ).…”

Section: Effects Of Shock Waves On Soft Tissuesmentioning

confidence: 99%

“…These may involve alterations in the permeability of cell membranes preventing the development of potentials to transmit painful stimuli, direct suppressive effects on nociceptors and a hyperstimulation mechanism which blocks the gate control mechanism, 23,24,29 but these possibilities remain speculative.…”

Section: Proposed Mechanisms For Explanation Of Clinical Benefitmentioning

confidence: 99%

Extracorporeal shock-wave therapy in the management of chronic soft-tissue conditions

Speed

2004

The Journal of Bone and Joint Surgery. British volume

115

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“…Letztere steht im Vordergrund und umfasst die Differenzierung von mesenchymalen Stammzellen bei gleichzeitig erhöhter TGF-β1-Produktion nach ESWT-Applikation [34]. Neben der Beeinflussung von osteogenen Transkriptionsfaktoren [33] sind eine erhöhte mRNA-Expression von "bone morphogenetic proteins" nachgewiesen sowie eine Verbesserung der Angiogenese [32,35]. In diesem Zusammenhang konnte eine vermehrte Ausbildung von Kapillargefäßen und Arteriolen 4 Wochen und 8 Wochen nach ESWT im Vergleich zur Kontrollgruppe beobachtet werden [32].…”

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“…Neben der Beeinflussung von osteogenen Transkriptionsfaktoren [33] sind eine erhöhte mRNA-Expression von "bone morphogenetic proteins" nachgewiesen sowie eine Verbesserung der Angiogenese [32,35]. In diesem Zusammenhang konnte eine vermehrte Ausbildung von Kapillargefäßen und Arteriolen 4 Wochen und 8 Wochen nach ESWT im Vergleich zur Kontrollgruppe beobachtet werden [32]. Im Gegensatz zur Ultraschalltherapie treten bei der Stoßwellenbehand-lung weitere indirekte Effekte vermehrt in den Vordergrund.…”

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