Shigella bacteraemia in adults

Abstract

Summary: Shigella infections are usually restricted to the intestine. There are few reports of Shigella isolated from the blood and most of these are from children, usually in neonates and the malnourished. In the small number of adult cases of Shigella bacteraemia which have been reported, there appears to be an association with underlying disease and immunosuppression including acquired immunodeficiency syndrome.We report three adult cases in which Shigella were isolated from blood. Two of these patients made an uneventful recovery whilst the third died. An underlying cause of immunosuppression was suspected in this patient but unproven.

Pneumonia complicating Shigella sonnei dysentery in an HIV-infected adult male

“…Bacteraemia/ septicaemia appears more common in elderly, or immunosuppressed patients. [5][6][7][8] Case reports describing isolation of S. sonnei in the sputum of an adult 11 and a child 12 with shigella dysentery add to the hypothesis that pneumonia complicating shigella dysentery may arise by haematogenous dissemination in some patients. Despite the negative culture of sputum and blood, it is possible in the patient described here that pulmonary infection arose via the haematogenous route.…”

Evaluation of the Types of Bacteria in the Blood of HIV-1 Patients Attending ART Clinic at the FMC Owo, Nigeria and their Antibiogram Profile

“…This is also an indicator to the increasing rate of Shigella bacteraemia. According to the findings of Trevett et al [11], the presence of Shigella bacteraemia occurs usually in adults with underlying disease conditions, such as leukaemia, diabetes, sickle cell anaemia, cirrhosis and HIV. Kotloff et al [12] also submitted that HIV infected individuals are at high risk of recurrent, severe and fatal occurrences of Shigella bacteremia.…”

Efficacy of Early Pegylated Interferon α‐2b Monotherapy for Acute Hepatitis C in HIV‐Infected Patients

“…mia [1,[3][4][5][6][7][8][9][10], all patients had preceding diarrhea (88.9%) or abdominal pain (11.1%). In contrast, our patient did not present with any symptom or sign that suggested preceding gastrointestinal infection.…”