Shifting archetype to nature’s hidden gems: from sources, purification to uncover the nutritional potential of bioactive peptides

Manzoor, Madhiya; Mir, Rakeeb Ahmad; Farooq, Asmat; Hami, Ammarah; Pakhtoon, Mohammad Maqbool; Sofi, Sajad Ahmad; Malik, Firdose Ahmad; Hussain, Khursheed; Bhat, M. Ashraf; Najeeb, S.; Pandey, Anamika; Khan, Mohd. Kamran; Hamurcu, Mehmet; Zargar, Sajad Majeed

doi:10.1007/s13205-023-03667-z

Cited by 1 publication

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References 149 publications

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“…As per the reports of the World Health Organization (WHO), human beings are paying most of their attention to the use of herbal medicines as they have the least side effects [ 90 , 91 ]. A huge number of medicinal plants are currently being investigated to explore natural products as the best alternative to unsafe drugs [ 92 , 93 , 94 ]. Regardless of the growth in recent diagnostics and treatment strategies, the prevalence of diseases at the global level is still rising.…”

Section: Role Of Saffron Bioactive Compounds Against Human Diseasesmentioning

confidence: 99%

Saffron, a Potential Bridge between Nutrition and Disease Therapeutics: Global Health Challenges and Therapeutic Opportunities

Mir,

Tyagi,

Hussain

et al. 2024

Plants

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Plants are an important source of essential bioactive compounds that not only have a beneficial role in human health and nutrition but also act as drivers for shaping gut microbiome. However, the mechanism of their functional attributes is not fully understood despite their significance. One such important plant is Crocus sativus, also known as saffron, which possesses huge medicinal, nutritional, and industrial applications like food and cosmetics. The importance of this plant is grossly attributed to its incredible bioactive constituents such as crocins, crocetin, safranal, picrocrocin, and glycosides. These bioactive compounds possess a wide range of therapeutic activities against multiple human ailments. Since a huge number of studies have revealed negative unwanted side effects of modern-day drugs, the scientific communities at the global level are investigating a large number of medicinal plants to explore natural products as the best alternatives. Taken into consideration, the available research findings indicate that saffron has a huge scope to be further explored to establish alternative natural-product-based drugs for health benefits. In this review, we are providing an update on the role of bioactive compounds of saffron as therapeutic agents (human disorders and antimicrobial activity) and its nutritional values. We also highlighted the role of omics and metabolic engineering tools for increasing the content of key saffron bioactive molecules for its mass production. Finally, pre-clinical and clinical studies seem to be necessary to establish its therapeutic potential against human diseases.

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Section: Role Of Saffron Bioactive Compounds Against Human Diseasesmentioning

confidence: 99%

Saffron, a Potential Bridge between Nutrition and Disease Therapeutics: Global Health Challenges and Therapeutic Opportunities

Mir,

Tyagi,

Hussain

et al. 2024

Plants

Self Cite

View full text Add to dashboard Cite

show abstract

Shifting archetype to nature’s hidden gems: from sources, purification to uncover the nutritional potential of bioactive peptides

Cited by 1 publication

References 149 publications

Saffron, a Potential Bridge between Nutrition and Disease Therapeutics: Global Health Challenges and Therapeutic Opportunities

Saffron, a Potential Bridge between Nutrition and Disease Therapeutics: Global Health Challenges and Therapeutic Opportunities

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