Shift workers in health care: endocrine age-related mechanisms of morbidity and mortality in the onto pathogenic model

Abstract

The mini-review is presented on the role of stress mediators and melatonin in age-related morbidity and mortality, as referred to shift work in health care. A short discussion at the end of the article concerns with the ways of confronting a challenge of information overload, greatly amplified during the last years of Covid-19 pandemics. A conclusion is made on the necessity of expanding the research on stress proteins in association with processes of tiredness and fatigue, as well as in sleepiness.