Sheep linkage mapping: nineteen linkage groups derived from the analysis of paternal half-sib families.

Abstract

Nineteen linkage groups containing a total of 52 markers have been identified in the sheep genome after typing large paternal half-sib families. The linkage groups range in size from 2 markers showing no recombination to a group containing 6 markers covering approximately 30 cM of the sheep genome. Thirteen of the groups have been assigned to a sheep chromosome. Three groups contain markers from bovine syntenic groups U2, U7 and U29, and one other group contains a marker that has been mapped only in humans. The remaining three groups are unassigned. This information will provide a useful foundation for a genetic linkage map of sheep.

Review regarding the genomic evolution in sheep milk production and their application to improve the selection criteria

“…Sheep genome was first developed starting with information about gene map and research for the identification of gene markers location on each chromosomes using in situ hybridization, Di Meo et al, (2007) and somatic cell hybrid panels, Burkin et al, (1997). Next step to follow in sheep genome was the linkage discovered behind genes maping starting in 1994 with 19 linkage groups with 52 markers and candidate genes RFLP, (Crawford et al 1994). Booroola fecundity gene was mapped by sheep genome scanning, (Montgomery et al, 1993).…”

Transparent vertebrates and their genetic images.

“…KING et al (1991) and MALO et al (1993)l. One wonders to how many non-human mammals these methods of molecular genetics will be extended in the upcoming few decades; note that an initial genetic map of the sheep is reported in this issue of GENETICS (CRAWFORD et al, 1994). The major improvements in the creation of the genetic image of the mouse are joined by important technical improvements in the molecular description of the embryo by wholemount hybridization in situ (see WILKINSON 1992).…”

Γενετική της τσιπούρας (Sparus aurata). Μελέτη των μικροδορυφορικών αλληλουχιών και χρήση τους στην εκτίμηση γενετικών παραμέτρων της αύξησης και άλλων ποσοτικών χαρακτήρων

“…Μια άλλη, εξίσου σημαντική, εφαρμογή της χαρτογράφησης είναι η επιλογή βασιζόμενη σε σημαντές (marker-based ή markerassisted selection) σύμφωνα με την οποία μπορούμε να ανιχνεύσουμε γονίδια που συμβάλλουν στη δημιουργία της γενετικής παραλλακτικότητας ενός ποσοτικού χαρακτήρα, πχ. του βάρους, και να εντοπιστεί εκείνο το αλληλόμορφο που έχει τη μέγιστη επίδραση στον υπό μελέτη χαρακτήρα (Botstein et al 1980, Lander & Botstein 1989, Georges et al 1990, Zhang & Smith 1992, Knott & Haley 1992, Cheverud & Routman 1993, Crawford et al 1994, Xu & Atchley 1995, Keightley et al 1996, Falconer & Mackay 1996, Hoeschele et al 1997, Hospital & Charcosset 1997, Whittaker et al 1997 (Davis 1988). Είναι κυρίως μοναχικό ψάρι, ενώ σε μερικές περιπτώσεις σχηματίζει ομάδες.…”