Sheehan's syndrome expected prevalence in five years in Mexico

Abstract

Background: Sheehan's syndrome (SS) occurs as result of ischemic pituitary necrosis due to postpartum hemorrhage.
 Objective: To calculate the approximate number of SS cases in Mexico and to determine an screening option.
 Methods: A search was performed in PubMed, Web of Science and Google Scholar of published papers in English, and Spanish using the terms: "obstetric hemorrhage" OR "postpartum hemorrhage" OR "Sheehan in pregnancy" AND "INEGI" OR "Incidence of Sheehan's syndrome". It was calculated the estimated cases of obstetric hemorrhage and the SS incidence based on casuistries from three countries.
 Results: Extrapolating data from India, the total cases of SS in Mexico in the last five years could be as high as 322761 or about 2000 if taking Iceland’s statistics. As the measure of all the adenohypophyseal hormones is of 56 dollars in Mexican public institutions, the option to make and early SS diagnosis should be to quantify only TSH that has a cost of 13.5 dollars.
 Conclusions: SS could be a highly prevalent disease in Mexico and the TSH quantification is a feasible tool to make a massive first line screening in those women with obstetric hemorrhage grade III o IV.