Shear wave elastography and transient elastography in HCV patients after direct-acting antivirals

Argalia, Giulio; Tarantino, Giuseppe; Ventura, Claudio; Campioni, Daniele; Tagliati, Corrado; Guardati, P.; Kostandini, Alba; Marzioni, Marco; Giuseppetti, Gian Marco; Giovagnoni, Andrea

doi:10.1007/s11547-020-01326-4

Cited by 27 publications

(26 citation statements)

References 24 publications

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“…Both US-LI-RADS and diagnostic LI-RADS do not address patients with vascular causes of liver cirrhosis (e.g., cardiac hepatopathy, Budd–Chiari syndrome) because these conditions are associated with hypervascular benign liver lesions, which increase the risk of false positives and reduce the PPV for the diagnosis of HCC [ 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 ]. Although with some regional differences, patients with hepatitis C in the absence of cirrhosis and adults with nonalcoholic steatohepatitis are not included in the screening.…”

Section: Li-radsmentioning

confidence: 99%

A Narrative Review on LI-RADS Algorithm in Liver Tumors: Prospects and Pitfalls

et al. 2022

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Liver cancer is the sixth most detected tumor and the third leading cause of tumor death worldwide. Hepatocellular carcinoma (HCC) is the most common primary liver malignancy with specific risk factors and a targeted population. Imaging plays a major role in the management of HCC from screening to post-therapy follow-up. In order to optimize the diagnostic-therapeutic management and using a universal report, which allows more effective communication among the multidisciplinary team, several classification systems have been proposed over time, and LI-RADS is the most utilized. Currently, LI-RADS comprises four algorithms addressing screening and surveillance, diagnosis on computed tomography (CT)/magnetic resonance imaging (MRI), diagnosis on contrast-enhanced ultrasound (CEUS) and treatment response on CT/MRI. The algorithm allows guiding the radiologist through a stepwise process of assigning a category to a liver observation, recognizing both major and ancillary features. This process allows for characterizing liver lesions and assessing treatment. In this review, we highlighted both major and ancillary features that could define HCC. The distinctive dynamic vascular pattern of arterial hyperenhancement followed by washout in the portal-venous phase is the key hallmark of HCC, with a specificity value close to 100%. However, the sensitivity value of these combined criteria is inadequate. Recent evidence has proven that liver-specific contrast could be an important tool not only in increasing sensitivity but also in diagnosis as a major criterion. Although LI-RADS emerges as an essential instrument to support the management of liver tumors, still many improvements are needed to overcome the current limitations. In particular, features that may clearly distinguish HCC from cholangiocarcinoma (CCA) and combined HCC-CCA lesions and the assessment after locoregional radiation-based therapy are still fields of research.

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Section: Li-radsmentioning

confidence: 99%

A Narrative Review on LI-RADS Algorithm in Liver Tumors: Prospects and Pitfalls

et al. 2022

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“…Another advanced US application that can improve image-guided IO is represented by elastography [ 52 , 53 ]: this rapidly evolving US technology provides information on tissues’ mechanical characteristics, such as their hardness or stiffness. This information can be used to plan liver- and renal-targeted biopsy to select the most suitable tissue/lesion regions and avoid areas at higher risk of post-biopsy bleedings [ 41 ].…”

Section: Imaging Modalitiesmentioning

confidence: 99%

Precision Imaging Guidance in the Era of Precision Oncology: An Update of Imaging Tools for Interventional Procedures

Floridi

Cellina

Irmici

et al. 2022

JCM

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Interventional oncology (IO) procedures have become extremely popular in interventional radiology (IR) and play an essential role in the diagnosis, treatment, and supportive care of oncologic patients through new and safe procedures. IR procedures can be divided into two main groups: vascular and non-vascular. Vascular approaches are mainly based on embolization and concomitant injection of chemotherapeutics directly into the tumor-feeding vessels. Percutaneous approaches are a type of non-vascular procedures and include percutaneous image-guided biopsies and different ablation techniques with radiofrequency, microwaves, cryoablation, and focused ultrasound. The use of these techniques requires precise imaging pretreatment planning and guidance that can be provided through different imaging techniques: ultrasound, computed tomography, cone-beam computed tomography, and magnetic resonance. These imaging modalities can be used alone or in combination, thanks to fusion imaging, to further improve the confidence of the operators and the efficacy and safety of the procedures. This article aims is to provide an overview of the available IO procedures based on clinical imaging guidance to develop a targeted and optimal approach to cancer patients.

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“…Thanks to the multiparametric approach, the exceptional contrast resolution and the possibility to exploit several advanced sequences, magnetic resonance imaging is the diagnostic gold standard for the study, characterization and follow-up of extra-abdominal DTs, with a pivotal role for intra-abdominal ones [ 138 , 139 , 140 , 141 , 142 , 143 ]. Most advantages are evident in particular extra-abdominal lesions occurring in the extremities, head and neck, abdominal and chest wall and in lesions at mesenteric localization in patients allergic to contrast agents or in young patients to reduce radiation exposure [ 1 , 7 , 21 ]. The signal intensity of MRI reflects the proportion of collagen fibers, spindle cells and extracellular matrix present and varies with imaging sequences.…”

Section: Magnetic Resonance Imaging Assessmentmentioning

confidence: 99%

“…According to the World Health Organization (WHO), DT is a “clonal fibroblastic proliferation that arises in the deep soft tissues and is characterized by infiltrative growth and a tendency toward local recurrence but an inability to metastasize”, even though it may be multifocal in the same limb or body part [ 1 ]. Although histopathological analysis represents the gold standard for diagnosis [ 1 , 2 , 3 ], imaging represents a necessary tool during the multidisciplinary approach to these tumors since it allows, thanks to the possibility of multimodality assessment (ultrasound (US), computed tomography (CT) and Magnetic Resonance Imaging (MRI)) [ 4 , 5 , 6 , 7 , 8 , 9 , 10 ], the detection, localization and evaluation of adjacent structures involvement, to establish a differential diagnosis so as to guide management (surgical or minimal invasive) [ 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 ].…”

Section: Introductionmentioning

confidence: 99%

Multimodality Imaging Assessment of Desmoid Tumors: The Great Mime in the Era of Multidisciplinary Teams

Simonetti

Bruno

Fusco

et al. 2022

JPM

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Desmoid tumors (DTs), also known as desmoid fibromatosis or aggressive fibromatosis, are rare, locally invasive, non-metastatic soft tissue tumors. Although histological results represent the gold standard diagnosis, imaging represents the fundamental tool for the diagnosis of these tumors. Although histological analysis represents the gold standard for diagnosis, imaging represents the fundamental tool for the diagnosis of these tumors. DTs represent a challenge for the radiologist, being able to mimic different pathological conditions. A proper diagnosis is required to establish an adequate therapeutic approach. Multimodality imaging, including ultrasound (US), computed tomography (CT) and Magnetic Resonance Imaging (MRI), should be preferred. Different imaging techniques can also guide minimally invasive treatments and monitor their effectiveness. The purpose of this review is to describe the state-of-the-art multidisciplinary imaging of DTs; and its role in patient management.

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Shear wave elastography and transient elastography in HCV patients after direct-acting antivirals

Cited by 27 publications

References 24 publications

A Narrative Review on LI-RADS Algorithm in Liver Tumors: Prospects and Pitfalls

A Narrative Review on LI-RADS Algorithm in Liver Tumors: Prospects and Pitfalls

Precision Imaging Guidance in the Era of Precision Oncology: An Update of Imaging Tools for Interventional Procedures

Multimodality Imaging Assessment of Desmoid Tumors: The Great Mime in the Era of Multidisciplinary Teams

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