Artificial
sensory afferent nerves that emulate receptor nanochannel
perception and synaptic ionic information processing in chemical environments
are highly desirable for bioelectronics. However, challenges persist
in achieving life-like nanoscale conformal contact, agile multimodal
sensing response, and synaptic feedback with ions. Here, a precisely
tuned phase transition poly(N-isopropylacrylamide)
(PNIPAM) hydrogel is introduced through the water molecule reservoir
strategy. The resulting hydrogel with strongly cross-linked networks
exhibits excellent mechanical performance (∼2000% elongation)
and robust adhesive strength. Importantly, the hydrogel’s enhanced
ionic conductance and heterogeneous structure of the temperature-sensitive
component enable highly sensitive strain information perception (GFmax = 7.94, response time ∼ 87 ms), temperature information
perception (TCRmax = −1.974%/°C, response time
∼ 270 ms), and low energy consumption synaptic plasticity (42.2
fJ/spike). As a demonstration, a neuromorphic sensing–synaptic
system is constructed integrating iontronic strain/temperature sensors
with fiber synapses for real-time information sensing, discrimination,
and feedback. This work holds enormous potential in bioinspired robotics
and bioelectronics.