Shanghai Fever in a Healthy Infant

Pseudomonas aeruginosa septicemia with intestinal necrosis in an infant – Shanghai fever

“…Nearly 80% of the patients exhibit this triad. [1][2][3] The gastrointestinal involvement can progress to bowel perforation secondary to patchy necrotizing enteritis. Necrotic patches in the oral cavity and the skin, the latter known as ecthyma gangrenosum, are frequently seen.…”

“…Meningitis, acute otitis media, eye discharge and facial paralysis have been some of the features in the reported cases. [1][2][3][4] The disease has been mainly reported from China, Hing Kong and Taiwan. This is the first report of Shanghai fever from Malaysia and to our knowledge has not been reported from any of the Association of South East Asian nations.…”

“…[1][2][3][4] Most infants with Shanghai fever were healthy prior to the disease. [1][2][3][4] Transient leucopenia was noted in about 60% while immunoglobulin and lymphocyte sub-population studies did not show primary immune deficiency in the Taiwan patients. 1 The WBC count normalised in our patient with infection control.…”

“…The features of the 27 patients of Shanghai fever from Taiwan, two patients from India, one from Brazil and the current patient are summarised in Table 1. [1][2][3][4] 90% of patients from Taiwan were below 1 year of age making it the main identifiable predisposing factor. 1 Mucus and blood in the stool were seen in 41% and 26%, respectively.…”

“…Perforations commonly involved the small bowel, mainly distal ileum and less commonly the colon. [1][2][3][4] Most infants with Shanghai fever were healthy prior to the disease. [1][2][3][4] Transient leucopenia was noted in about 60% while immunoglobulin and lymphocyte sub-population studies did not show primary immune deficiency in the Taiwan patients.…”