Sexually Transmitted Infections Among US Women and Men

Satterwhite, Catherine Lindsey; Torrone, Elizabeth; Meites, Elissa; Dunne, Eileen F.; Mahajan, Reena; Ocfemia, M. Cheryl Bañez; Su, John R.; Xu, Fujie; Weinstock, Hillard

doi:10.1097/olq.0b013e318286bb53

Cited by 1,171 publications

(900 citation statements)

References 27 publications

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“…Such HRSB in teenagers can have serious consequences, including sexually transmitted infections and unwanted pregnancies, 2 which result in tremendous costs to individuals and society. 3,4 Despite public health concern surrounding adolescent HRSB and teen pregnancy, little is known about developmental pathways preceding adolescent HRSB.…”

Section: Resultsmentioning

confidence: 99%

Developmental Pathways to Sexual Risk Behavior in High-Risk Adolescent Boys

Sitnick¹,

Brennan²,

Forbes

et al. 2014

Pediatrics

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WHAT'S KNOWN ON THIS SUBJECT: Investigations of adolescents' sexual risk behavior have focused on factors such as parental monitoring, deviant peer affiliation, and daring that occur during early and midadolescence. Less is known about early childhood precursors to adolescent sexual risk behavior. WHAT THIS STUDY ADDS:This prospective longitudinal study identifies parenting practices and mothers' depressive symptomatology during early childhood as precursors to later sexual risk behavior and involvement in pregnancy in adolescent boys, with deviant peer affiliation during emerging adolescence mediating these relationships. abstract OBJECTIVE: Adolescent boys' involvement in pregnancy and sexual risk behavior is a public health concern. Although research has identified predictors of sexual risk behavior during adolescence, few studies have investigated precursors to boys' sexual risk behavior beginning in early childhood, the identification of which could serve to inform interventions and help reduce involvement in pregnancy. Our goal was to identify early developmental pathways associated with sexual risk behavior in a sample of low-income adolescent boys. METHODS:Data from a prospective longitudinal study in 310 at-risk boys were used to examine externalizing problems, mothers' depressive symptoms, and low-nurturant parenting in early childhood (1.5, 2, and 3.5 years old) and daring, externalizing, parental monitoring, and deviant peer affiliation during emerging adolescence (11 and 12 years old) as precursors of sexual risk behavior between the ages 15 and 20 years. Structural equation modeling was used to explore pathways associated with later high-risk sexual behavior (HRSB). RESULTS:In multivariate analyses, adolescent daring and deviant peer affiliation at age 12 were associated with later HRSB. Furthermore, deviant peer affiliation during emerging adolescence mediated the relationship between mothers' depressive symptoms and nurturant parenting during early childhood and later adolescent HRSB. CONCLUSIONS:Family-based risk factors in early childhood are predictive of HRSB in adolescence but are also influenced, and in some cases mediated, by relationships with peers and child characteristics during emerging adolescence.

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Section: Resultsmentioning

confidence: 99%

Developmental Pathways to Sexual Risk Behavior in High-Risk Adolescent Boys

Sitnick¹,

Brennan²,

Forbes

et al. 2014

Pediatrics

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“…Всебічно проаналізовані фактори, що впливають на поширення цих недуг [3]. Детально описано епідеміологічну ситуацію стосовно сифілі-су в країнах Європейського Союзу та Сполучених Штатах Америки [4].…”

Section: обґрунтування дослідженняunclassified

“…Спустя два года была опубликована стратегия профилактики новых случаев инфициро-вания ВИЧ у детей грудного и раннего возраста [2]. Согласно определению ВОЗ, ликвидация означает со-кращение до нуля числа новых случаев заболевания на определенной территории [3]. Однако в силу того, что ВИЧ-инфекция и сифилис остаются проблемой общественного здравоохранения, а эффективность мероприятий по профилактике передачи от матери ребенку (ППМР) инфекций является хотя и высокой, но в настоящее время невозможно сократить ее до нуля.…”

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Analysis of syphlis incidence in Zhytomyr region

Fomiuk¹,

Krukovska²,

Косенко³

2017

ScienceRise: Medical Science

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“…10-12 Human papillomavirus infection is the most common sexually transmitted infection in the US and usually clears spontaneously within 2 years via local cell mediated immunity in the cervix. 13 , 14 High risk HPV types have a tendency to persist in cervical tissue and integrate into host DNA which leads to oncogene overexpression and neoplastic transformation. 15 There are several high risk HPV types, of which types 16 and 18 account for approximately 70% of all cervical cancer cases in the general population.…”

Section: Introductionmentioning

confidence: 99%

The effect of history of abnormal pap smear or preceding HPV infection on the humoral immune response to Quadrivalent Human Papilloma virus (qHPV) vaccine in women with systemic lupus erythematosus

Dhar

Essenmacher

Dhar

et al. 2018

Human Vaccines & Immunotherapeutics

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Objective : To determine if natural human papillomavirus (HPV) infection would induce an anamnestic response to quadrivalent (qHPV) vaccine in women with Systemic Lupus Erythematosus (SLE). Methods: Thirty four women (19-50 years) with mild to moderate and minimally active or inactive SLE received standard qHPV vaccine. Neutralizing antibody titers to HPV 6, 11, 16 and18 were evaluated pre- and post- vaccine using HPV competitive Luminex Immunoassay. For each HPV type, logistic regressions were performed to explore the relationship between a positive titer at baseline with their final geometric mean titer and with the rise in titer. Fisher's Exact Test was used to assess the association of at least one positive HPV antibody test at baseline and history of abnormal pap. Results: History of abnormal pap smear/cervical neoplasia occurred in 52.9%. Baseline anti HPV antibody titers: 21% = negative for all 4 HPV types, 79% = positive for ≥1 of the HPV types. Statistical analysis showed: those with a history of abnormal pap smear/cervical neoplasia were likely to have a positive anti-HPV antibody result pre-vaccine to ≥ 1 of the 4 types, p = 0.035 Fisher's Exact Test. In general, HPV exposed women showed higher post vaccine GMTs than HPV unexposed women with higher point estimates. However, when examining the rise in titers using logistic regression, there was no evidence of an anamnestic response. Conclusion: Prior HPV infection and cervical neoplasia in SLE are linked with no anamnestic response to HPV vaccine. This supports not checking HPV-antibodies pre-vaccine. Women with SLE should be vaccinated for HPV.

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Sexually Transmitted Infections Among US Women and Men

Abstract: Sexually transmitted infections are common in the United States, with a disproportionate burden among young adolescents and adults. Public health efforts to address STIs should focus on prevention among at-risk populations to reduce the number and impact of STIs.

Cited by 1,171 publications

References 27 publications

Developmental Pathways to Sexual Risk Behavior in High-Risk Adolescent Boys

Developmental Pathways to Sexual Risk Behavior in High-Risk Adolescent Boys

Analysis of syphlis incidence in Zhytomyr region

The effect of history of abnormal pap smear or preceding HPV infection on the humoral immune response to Quadrivalent Human Papilloma virus (qHPV) vaccine in women with systemic lupus erythematosus

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