Sexual and reproductive health is at the base of people's living and wellbeing, the ability to develop in a supportive environment and grow into sexually responsive and responsible adults, the ability to enjoy one's sexuality without harming or damaging oneself or one's partner, are among the unique attributes that define us as human. Many of the typical changes that occur during adolescence tend to interfere with the effectiveness and amount of interaction between parent and child. The objective of the study is to assess communication on sexual and reproductive health issues among Mizan secondary and preparatory school students with parents. Institution based cross sectional quantitative study design was conducted among Mizan secondary and preparatory school students with sample size of 356 and total population of 3436 from April, 20/4/2016 to April, 25/4/2016. The data was collected by using structured self-administered questionnaires. After the data was collected it was processed and analyzed manually by the help scientific calculator. The response rate was 100%. From the total of three hundred fifty six respondents 196(55.1%) of them were females. One hundred three 103(28.9%) of respondents were discussed at least one SRH issue with parents for the last 12 month of the study period, from those 58(56.3%) of them were females and 45(43.7%) of them were males. but majority 253(71.1%) of them didn't discussed about SRH issues with their parents. This study shows that student-parent communication on SRH issues is low, only less than one-third of the students were communication SRH. The risk for SRH problems need urgent and continues intervention as such it is necessary to equip and educate parents and students on different sexual and reproductive health issues. Therefore; there should be give school base sex education about SRH and youth friendly health service for youth and adolescents at different level of health care.