Sexual Life of Women With Mayer-Rokitansky-Küster-Hauser Syndrome After Laparoscopic Vecchietti Vaginoplasty

Abstract

IntroductionAdequate anatomic and physiologic functions of the genitalia are fundamental prerequisites for sexual well-being and reproduction. Mayer-Rokitansky-Küster-Hauser syndrome (MRKHS) compromises female sexual life and makes reproduction impossible.AimTo assess the psychosexual effect of vaginal reconstruction using the laparoscopic Vecchietti technique in patients with MRKHS.MethodsForty-two patients with MRKHS who underwent laparoscopic Vecchietti vaginoplasty were included. Their partners also were interviewed. A control group of 45 age-matched, childless, sexually active women were examined during the same period.Main Outcome MeasuresA gynecologic examination was performed to determine the anatomic outcome. Psychosexual function was evaluated with the Female Sexual Distress Scale–Revised (FSDS-R), the Female Sexual Function Index (FSFI), and a semistructured interview. Genital self-image was evaluated using the Female Genital Self-Image Scale (FGSIS).ResultsAverage neovagina length (7.0 ± 9.6 cm) in the MRKHS group was significantly shorter than the vaginal length in the control group (9.3 ± 2.5 cm). Women with a neovagina reported satisfactory sexual function (FSFI score = 29 ± 2.7) that was not significantly different from the control group (P < .05); however, they also had significantly higher levels of distress (FSDS-R score = 14.5 ± 6.5) and were not satisfied with their genitals (FGSIS score = 22.0 ± 2.4) compared with the control group.ConclusionSexual function in women with MRKHS can be restored successfully by vaginoplasty; however, they have higher rates of distress and are less satisfied with their genitals.Pastor Z, Fronĕk J, Nováčková M, Chmel R. Sexual Life of Women With Mayer-Rokitansky-Küster-Hauser Syndrome After Laparoscopic Vecchietti Vaginoplasty. Sex Med 2017;5:e106–e113.

Revaluation and lessons learned from the first 9 cases of a Czech uterus transplantation trial: Four deceased donor and 5 living donor uterus transplantations

“…8,9 In vitro fertilization (IVF) treatments using the long gonadotropin-releasing hormone (GnRH) agonist protocol preceded UTx. The recipients underwent meticulous examination before UTx, including examination of quality of their sexual life and a 4-stage screening process with an explanation of the risks and benefits regarding the entire experimental treatment for AUFI.…”

“…The recipients underwent meticulous examination before UTx, including examination of quality of their sexual life and a 4-stage screening process with an explanation of the risks and benefits regarding the entire experimental treatment for AUFI. 8,9 In vitro fertilization (IVF) treatments using the long gonadotropin-releasing hormone (GnRH) agonist protocol preceded UTx. The protocol was initiated with downregulation using depot GnRH agonist in the absence of a growing follicle.…”

“…10.7 days(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22). The mean surgical time for the UTx was 245 minutes (210-300 minutes).…”

“…The mean postoperative hospital stay was 8 days(6)(7)(8)(9)(10)(11), and the mean surgical time for graft procurement was 356 minutes (320-430). The mean postoperative hospital stay was 8 days(6)(7)(8)(9)(10)(11), and the mean surgical time for graft procurement was 356 minutes (320-430).…”

Seguridad y eficacia de la vaginoplastia de Vecchietti en agenesia vaginal: estudio de cohorte, en Medellín, Colombia, 2007 a 2012

“…Respecto a la funcionalidad, nuestros resultados son similares a los informados por Pastor et al en 42 casos intervenidos con la TVV, en los que informan una adecuada función sexual según el Índice de función sexual femenina (15).…”