Sexual Dysfunctions in Parkinson's Disease: An Underrated Problem in a Much Discussed Disorder

Bhattacharyya, Kalyan B; Rosa-Grilo, Miguel

doi:10.1016/bs.irn.2017.05.019

Cited by 37 publications

(30 citation statements)

References 88 publications

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“…Regarding the variables that can affect the quality of life (QoL) and satisfaction of individuals with Parkinson's disease (PD), sexual disorders assume their importance because they are of nonmotor symptoms (NMSs), those that stand out are the most neglected NMSs in this disease 1,2 and that cause harm and distress in both men and women. 3e6 According to the World Health Organization (WHO) (2006), 7 sexual health is a fundamental aspect of life, regardless of the presence of sexual dysfunction, and each individual has the right to conduct their relationships and have personal control over sexual and reproductive behavior with adequate information and treatment.…”

Section: Introductionmentioning

confidence: 99%

Sexual Disorders and Quality of Life in Parkinson's Disease

et al. 2021

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Introduction: Sexual disorders are the most neglected nonmotor symptoms in Parkinson's disease (PD). Although doctors seek greater priority to motor manifestations, which are the basis for the diagnosis of PD, the nonmotor symptoms deserve to be highlighted as much as the motor problems because of their strong presence and discomfort in the patients, causing the important impairment in the quality of life (QoL) of the individual with PD. Aim: Provide the prevalence of sexual disorders among patients with PD and alert the medical profession to investigate and be familiar with problems related to QoL and sexual disorders in PD. Methods: This is a large literature review on sexual disorders in PD and impaired QoL. Main Outcome Measures: Sexual disorders in PD and prevalence between genders have been described in epidemiological studies. Neuroanatomy, pathophysiology, risk factors, QoL, and etiologies were reviewed. Results: The estimate of the prevalence of sexual dysfunction in the form of compulsive sexual behavior in PD is higher in men by 5.2% than in women by 0.5%. This diagnosis is a determinant of intense and persistent suffering and is related to several health problems of a social, economic, personal, family, psychological, and occupational nature, which can even culminate in sexual abuse. It is most commonly associated with the use of drugs commonly used in PD therapy in 98.1% of cases. In addition to this serious public health problem, another common condition of sexual dysfunction occur with the decreased libido by loss of the neurotransmitter dopamine proper of the pathophysiology of PD. Conclusion: The presence of sexual disorders in PD should be tracked and monitored because of its harmful consequences, whether due to increased sexual behavior or associated psychological distress, as well as the impacts on QoL. Early recognition and adequate treatment of PD in its fullness and richness of associated symptoms are essential for improving QoL. Santa Rosa Malcher CM, Roberto da Silva Gonçalves Oliveira K, Fernandes Caldato MC, et al. Sexual Disorders and Quality of Life in Parkinson's Disease. Sex Med 2020;XX:XXXeXXX.

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Section: Introductionmentioning

confidence: 99%

Sexual Disorders and Quality of Life in Parkinson's Disease

et al. 2021

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“…Dopaminergic pathways responsible for erection and arousal are affected. ED is estimated to affect about 42.6% to 79% [ 19 ], while other aspects of sexual function are affected, such as libido, ejaculation and orgasm [ 20 ].…”

Section: Etiology Of Neurogenic Edmentioning

confidence: 99%

Neurogenic Erectile Dysfunction. Where Do We Stand?

Thomas¹,

Konstantinidis²

2021

Medicines

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Erectile Dysfunction (ED) is the persistent inability to attain and maintain an erection sufficient to permit satisfactory sexual performance, causing tremendous effects on both patients and their partners. The pathophysiology of ED remains a labyrinth. The underlying mechanisms of ED may be vasculogenic, neurogenic, anatomical, hormonal, drug-induced and/or psychogenic. Neurogenic ED consists of a large cohort of ED, accounting for about 10% to 19% of all cases. Its diversity does not allow an in-depth clarification of all the underlying mechanisms nor a “one size fits all” therapeutical approach. In this review, we focus on neurogenic causes of ED, trying to elucidate the mechanisms that lie beneath it and how we manage these patients.

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“…Zaburzenia seksualne to częsty objaw pacjentów z PD, zarówno kobiet, jak i mężczyzn [46]. Objawy te mogą dotyczyć zaburzeń popędu jak i czynności seksualnych.…”

Section: Zaburzenia Seksualneunclassified