Sexual Dysfunction in Women With Kidney Disease

Ali, Sehrish; Dave, Natasha

doi:10.1053/j.ackd.2020.07.005

Cited by 12 publications

(9 citation statements)

References 69 publications

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“…Sexual dysfunction in women with CKD is probably common and under-recognized; it involves hormonal imbalances as well as psychological issues [ 27–29 ]. Women with advanced CKD or kidney failure may have alterations in the hypothalamic–gonadal axis, causing menstrual irregularities, abnormal uterine bleeding, anovulation and early menopause (Fig.…”

Section: Sexual Dyfunction In Women Living With Ckdmentioning

confidence: 99%

“…Women with advanced CKD or kidney failure may have alterations in the hypothalamic–gonadal axis, causing menstrual irregularities, abnormal uterine bleeding, anovulation and early menopause (Fig. 3 ) [ 27–29 ]. Conversely, in the absence of specific treatments that may reduce fertility, the paradigm of which is cyclophosphamide for lupus nephropathy, fertility is probably not reduced in early CKD [ 27–30 ].…”

Section: Sexual Dyfunction In Women Living With Ckdmentioning

confidence: 99%

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Pre-gestational counselling for women living with CKD: starting from the bright side

Da Silva,

Orozco-Guillén,

Longhitano

et al. 2024

Clinical Kidney Journal

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Pregnancy in women living with chronic kidney disease (CKD) was often discouraged due to the risk of adverse maternal-fetal outcomes and the progression of kidney disease. This negative attitude has changed in recent years, with greater emphasis on patient empowerment than on the imperative “non nocere”. Although risks persist, pregnancy outcomes even in advanced CKD have significantly improved, both for the mother and the new-born. Adequate counselling can help to minimize risks and support a more conscious and informed approach to those that are unavoidable. Pre-conception counselling enables a woman to plan the most appropriate moment for her to try to become pregnant. Counselling is context sensitive and needs to be discussed also within an ethical framework. Classically, counselling is more focused on risks than on the probability of a successful outcome. “Positive counselling”, highlighting also the chances of a favourable outcome can help to strengthen the patient-physician relationship, which is a powerful means of optimizing adherence and compliance. Since, due to the heterogeneity of CKD, giving exact figures in single cases is difficult and may even be impossible, a scenario-based approach may help understanding and facing favourable outcomes and adverse events. Pregnancy outcomes modulate the future life of the mother and of her baby; hence the concept of “post partum” counselling is also introduced, discussing how pregnancy results may modulate the long-term prognosis of the mother and the child and the future pregnancies.

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Section: Sexual Dyfunction In Women Living With Ckdmentioning

confidence: 99%

Section: Sexual Dyfunction In Women Living With Ckdmentioning

confidence: 99%

Pre-gestational counselling for women living with CKD: starting from the bright side

Da Silva,

Orozco-Guillén,

Longhitano

et al. 2024

Clinical Kidney Journal

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“…Factors that may affect sexual function in the CKD population include the adverse psychosocial effects of having a chronic illness, depression, anxiety, and negative body image. 78,80,81 Physical challenges, such as decreased libido and vaginal lubrication, orgasmic impairment, and dyspareunia, are common among women with CKD, whereas comorbidities and sociodemographic factors can exacerbate the risk. 78,79,81,82 Kidney Disease and Sexually Transmitted Infections Youth aged 15 to 24 years account for approximately half of new sexually transmitted infection (STI) cases in the United States, 83,84 and it is estimated that 1 of 4 sexually active adolescent females have an STI, most often Chlamydia trachomatis infection and human papillomavirus (HPV) infection.…”

Section: Q3mentioning

confidence: 99%

Female Reproductive and Gynecologic Considerations in Chronic Kidney Disease: Adolescence and Young Adulthood

Chang

Dumanski

Ahmed

2022

Kidney International Reports

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Chronic kidney disease (CKD) increasingly affects younger people, including adolescents and young adults. CKD among females is accompanied by unique reproductive and gynecologic health concerns; though to date, this area has not been well studied. Hormonal disruptions attributed to CKD may underlie the high prevalence of abnormal uterine bleeding and influence the age of menarche in adolescents. Period poverty as a socioeconomic barrier further exacerbates the female-specific burdens of CKD. Reduced fertility in CKD is likely multifactorial and may be related to a reduction in ovarian reserve, reproductive hormone disturbances, and gonadotoxic medication use in addition to low sexual function and activity. Fertility, sexual function and activity, and risk of sexually transmitted infections increase with transplantation. Pregnancy is possible at any stage of CKD, although often accompanied by high risks of maternal and fetal complications. Contraception is thus an important consideration in CKD, but use is low and the risks and benefits of different forms in the setting of CKD are not well characterized. Though patients with CKD report reproductive health as an important element of care, many nephrologists report lack of confidence and training in this area, highlighting the need for targeted research and education. The unique reproductive health care needs of the growing transgender youth population warrant attention in nephrology training with multidisciplinary input. This review will discuss female reproductive health and gynecologic considerations in adolescents and young adults with CKD while proposing clinical and research strategies to improve this understudied yet important aspect of kidney care.

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“…Perico and Remuzzi reported in 2017 that about 10% of the world’s population is affected with CKD and millions die each year because of the unaffordability of its medical treatment [ 3 ]. If CKD is ignored, it can turn into a more serious condition called end-stage renal disease (ESRD), which can only be treated through costly procedures like hemodialysis or kidney transplant [ 4 ]. Studies report that ESRD derails many human physiological systems [ 5 - 6 ].…”

Section: Introductionmentioning

confidence: 99%

Revealing the Connection Between Hemodialysis and Sexual Physiology in Women With End-Stage Renal Disease

Rahman¹,

Ghani²,

Kausar³

et al. 2023

Cureus

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Introduction: In the recent past, the procedure of hemodialysis has frequently been opted for patients with end-stage renal disease (ESRD) around the globe. In such patients, the concern of sexual dysfunction is highly prevalent, which causes psychological as well as social deterioration in these patients. Wretchedly, this issue has been ignored in developing countries like Pakistan because of social and cultural constraints.Objectives: The aim was to measure and compare Female Sexual Functions of Dialysis (FSFI) scores among three comparative groups: healthy controls, pre-dialysis patients, and hemodialysis patients.Methods: A comparative cross-sectional study was carried out with 60 females aged 22-50 years in which 20 were healthy (controls) and 40 were patients with ESRD; of these 40, 20 were taking only oral medicines (pre-dialysis) and 20 were also receiving hemodialysis (hemodialysis). Married women who could read Urdu and were living with live spouses were included, and those with any psychological or psychiatric illness were excluded. Data was collected through a Likert-scaled questionnaire, Urdu translation of the FSFI questionnaire, and scores of each domain were analyzed. Single-tail one-way ANOVA was used to observe the significant difference among the three comparative groups.Results: A strong statistical difference was observed among the hemodialysis, pre-dialysis, and healthy control groups when these three study groups were compared for the mean scores of all related domains of FSFI questtionarie. In each female sexual domain, i.e. Desire, Arousal, Lubrication, Orgasm, Satisfaction, and Pain, the diseased groups (pre-dialysis and hemodialysis) showed lower sexual scores than the healthy group. The lowest scores were observed in the pre-dialysis group (16.4 ± 6.8) and the highest were noticed in the healthy group (29.9 ± 1.8); the hemodialysis group (23.3 ± 5.0) expressed a moderate pattern of scores in each sexual domain.Conclusion: ESRD female patients who were receiving hemodialysis along with routine oral medications showed improved sexual physiology (with better FSFI scores) compared to those who were without hemodialysis.

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Sexual Dysfunction in Women With Kidney Disease

Cited by 12 publications

References 69 publications

Pre-gestational counselling for women living with CKD: starting from the bright side

Pre-gestational counselling for women living with CKD: starting from the bright side

Female Reproductive and Gynecologic Considerations in Chronic Kidney Disease: Adolescence and Young Adulthood

Revealing the Connection Between Hemodialysis and Sexual Physiology in Women With End-Stage Renal Disease

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