Sexual Dysfunction in Multiple Sclerosis

Khan, Fary; Pallant, Julie; Ng, Louisa; Whishaw, Michael

doi:10.1007/s11195-011-9198-4

Cited by 22 publications

(12 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Another reason for such observation might be related to the small sample size of the study. Studying 73 MS patients a similar finding was reported by Khan et al where they have found no association between age and sexual dysfunction as measured by the Sexual Frequency Scale [23]. …”

Section: Discussionsupporting

confidence: 80%

Determinants of sexual dysfunction in women with multiple sclerosis

et al. 2013

View full text Add to dashboard Cite

BackgroundThe aim of present study was to determine disease-related and psychological risk factors for sexual dysfunction in women with multiple sclerosis (MS).MethodsThis was a clinical-based study conducted from September 2009 to June 2010 in Tehran, Iran. A consecutive sample of female patients with MS was recruited from an outpatient clinic. The Female Sexual Function Index (FSFI) was used to evaluate sexual function. In addition neurological impairment was measured using the Kurtzke Expanded Disability Status Scale (EDSS), and depression was assessed using the Beck Depression Inventory-II (BDI-II). Univariate and multiple logistic regression analyses were performed in order to examine the association between sexual dysfunction and independent variables.ResultsIn all, 226 women participated in the study. Of these, 125 women (55.3%) met the criteria for sexual dysfunction. The mean age of participants was 35.7 years (SD = 8.07). The results obtained from multiple logistic regression analysis indicated that the disease duration (OR for the disease duration of equal or greater than 9 years = 3.13, %95 CI = 1.29-7.57, P = 0.01), the disease course (OR for secondary progressive MS = 3.96, %95 CI = 1.55-10.10, P = 0.004) and the BDI score (OR = 1.11, %95 CI = 1.07-1.16, P < 0.001) were significant factors contributing to sexual dysfunction in these patients.ConclusionsThe findings from this study indicated that the duration and severity of the disease in addition to depression were the most significant factors that contributed to sexual dysfunction in women with multiple sclerosis. The burden of disease and sexual dysfunction suggests the need for further attention to this patient population.

show abstract

Section: Discussionsupporting

confidence: 80%

Determinants of sexual dysfunction in women with multiple sclerosis

et al. 2013

View full text Add to dashboard Cite

show abstract

“…Published studies show different findings regarding the relationship of the severity of MS symptoms and duration of the disease with SD, indicating either positive correlation [10,29] or no correlation [30]. Apart from weaker desire in older patients, we found that none of the three factors of patient age, time since diagnosis of MS, and EDSS score were independently correlated with the incidence or severity of SD.…”

Section: Discussioncontrasting

confidence: 66%

Sexual Dysfunctions and Sexual Quality of Life in Men with Multiple Sclerosis

Lew–Starowicz

Rola

2014

The Journal of Sexual Medicine

View full text Add to dashboard Cite

Introduction Multiple sclerosis (MS) is one of the most frequent diseases of the central nervous system and usually occurs at the age when people would be expected to be in the prime of their sexual lives. Clinicians working in this field commonly concentrate on the classical neurological deficits and often overlook symptoms that seriously affect the quality of life, such as sexual dysfunction (SD). Sexual functioning of MS patients remains poorly understood. Aim The aim of this study was to assess the prevalence of SDs, their relationship with demographic factors, and sexual quality of life in men with multiple sclerosis (MS). Methods Sixty-seven patients from the National Multiple Sclerosis Center were interviewed, completed the questionnaires, and underwent neurological assessment. Main Outcome Measures Primary outcome measures included the International Index of Erectile Function (IIEF), the Sexual Quality of Life Questionnaire (SQoL), and the Expanded Disability Status Scale (EDSS). Results The most common complaints were erectile dysfunction (52.9%), decreased sexual desire (26.8%), and difficulties in reaching orgasm (23.1%) or ejaculation (17.9%). The severity of SD had a clear impact on sexual quality of life, especially in the domains of erectile function and intercourse satisfaction. However, neither IIEF nor SQoL scores were correlated with age, time since onset of MS symptoms, or EDSS scores. Only 6% of the patients had ever discussed their concerns with a medical professional or undergone sexual therapy. Conclusions SD is highly prevalent but commonly overlooked in MS patients and has a significant impact on their sexual quality of life. The data support a multifactorial etiology of SD in MS. More focus on SD and use of appropriate screening tools in clinical practice with MS patients are recommended.

show abstract

“…fear from unwanted urination or defecation) during intercourse [10, 13]. In a recent study of 19 men and 52 women with MS by Khan and colleagues [14] significant negative correlations between the Total Personal Experiences Questionnaire (PEQ) Sexual Frequency scale and Neurological Disability Scale (ρ = −0.30) were found. The scores in the PEQ Sexual Frequency scale also correlated negatively with the Quality of life item from the American Urological Association Bladder score (ρ = −0.35) and with the MS Impact Scale Physical subscale (ρ = −0.30).…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Sexual Dysfunctions Among Women with Multiple Sclerosis

Lew–Starowicz

Rola

2013

Sex Disabil

View full text Add to dashboard Cite

Sexual concerns are known to be common in women suffering from multiple sclerosis (MS) but definite data on the prevalence of particular sexual dysfunctions (SD) remain unclear. Previous studies brought inconsistent findings and rely on small groups of patients or use of unvalidated assessment methods. The aim of this research was to evaluate the prevalence of SD in women with MS using validated clinimetric scales. 137 female inpatients with MS diagnosis were interviewed, completed The Female Sexual Function Questionnaire SFQ28 and underwent neurological assessment. Only 2.2 % of patients had ever discussed their sexual concerns with a physician. 70.1 % reported sexual activity. At least one SD could be found in 82.5 % of patients, hypoactive sexual desire (57.7 %), arousal dysfunction (decreased genital sensation in 47.3 %, decreased lubrication in 48.4 %, decreased subjective arousal in 45.2 %) and orgasmic dysfunction (39.8 %) being the most probable. SD were less likely in women who assessed their relationship positively but more common in older patients and those who had a positive history of depression. The prevalence of SD was higher comparing to the majority of studies by other authors. In conclusion, SD are very common in female patients with MS and permanently overlooked by medical professionals. Therefore, the assessment of sexual function should be implemented in all patients after the diagnosis of MS. Further research is needed for better understanding of the sexuality of this particular population in order to establish targets for therapeutic intervention.

show abstract

Sexual Dysfunction in Multiple Sclerosis

Cited by 22 publications

References 27 publications

Determinants of sexual dysfunction in women with multiple sclerosis

Determinants of sexual dysfunction in women with multiple sclerosis

Sexual Dysfunctions and Sexual Quality of Life in Men with Multiple Sclerosis

Prevalence of Sexual Dysfunctions Among Women with Multiple Sclerosis

Contact Info

Product

Resources

About