Sexual Dysfunction Among Patients With Chronic Kidney Disease

Wang, Connie J.; Cukor, Daniel; Johansen, Kirsten L.

doi:10.1016/j.semnephrol.2021.10.006

Cited by 7 publications

(6 citation statements)

References 145 publications

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“… 57 CKD significantly impacts the body’s hormonal balance, leading to various hormonal disturbances that can affect sexual function. 58 In CKD, the kidneys’ diminished ability to filter blood and regulate hormones, such as testosterone in men and estrogen in women, contributes to hormonal imbalances. These imbalances are associated with symptoms like reduced libido, erectile dysfunction in men, and menstrual irregularities in women, directly impacting sexual health and function.…”

Section: Discussionmentioning

confidence: 99%

Exploring Symptom Clusters in Chinese Patients with Diabetic Kidney Disease: A Network Analysis

Duan,

Liu,

et al. 2024

IJGM

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The research on symptom management in patients with diabetic kidney disease (DKD) has shifted from separate symptoms to symptom clusters and networks recently. This study aimed to evaluate the unpleasant symptoms of DKD patients, and to investigate how these symptom clusters could affect patients. Methods: 408 DKD patients were recruited in this cross-sectional study. The symptoms of DKD patients were measured using the modified Dialysis Symptom Index. Network analysis was employed to evaluate the symptom network and the characteristics of individual nodes, while factor analysis was utilized to identify symptom clusters. Results: Blurred vision was the most prevalent symptom among DKD patients. The symptoms identified as the most distressing, severe, and frequent were light headache or dizziness, arteriovenous fistula/catheterization pain, and diarrhea, respectively. Five symptom clusters were obtained from factor analysis, and the most central symptom cluster in the entire symptom network was sexual dysfunction. Conclusion:This study identified five symptom clusters in Chinese DKD patients, with sexual dysfunction emerging as the most central cluster. These findings carry significant clinical implications, underscoring the necessity of assessing symptom clusters and their associations to enhance symptom management in DKD patients. Further research is essential to elucidate the underlying mechanisms of symptoms and to clarify the associations among symptoms in DKD patients across different disease trajectories or treatment modalities.

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Section: Discussionmentioning

confidence: 99%

Exploring Symptom Clusters in Chinese Patients with Diabetic Kidney Disease: A Network Analysis

Duan,

Liu,

et al. 2024

IJGM

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Section: Introductionunclassified

“…Хроническая болезнь почек (ХБП) является распространенной проблемой, встречаясь более чем у 10 % населения, при этом ежегодно отмечается рост заболеваемости [1,2]. Наряду с почками поражаются многие другие жизненно важные органы и системы [1,3]. Среди различных осложнений ХБП эректильная дисфункция (ЭД) остается одной из значимых проблем, с которой, по данным разных авторов, сталкиваются от 70 до 86 % пациентов [1][2][3].…”

Section: Introductionunclassified

“…Наряду с почками поражаются многие другие жизненно важные органы и системы [1,3]. Среди различных осложнений ХБП эректильная дисфункция (ЭД) остается одной из значимых проблем, с которой, по данным разных авторов, сталкиваются от 70 до 86 % пациентов [1][2][3]. Сексуальные дисфункции отмечаются на ранних стадиях хронических заболеваний почек и в дальнейшем по мере снижения функции почек ухудшаются.…”

Section: Introductionunclassified

“…Сулейманов 1 , Э.И. Россошанская 1 1 Кафедра эндоскопической урологии и ультразвуковой диагностики факультета непрерывного медицинского образования медицинского института Российского университета дружбы народов (РУДН); Россия, 117198 Москва, ул. Миклухо-Маклая, 6; 2 ГУ «Республиканский научно-клинический центр урологии», Министерство здравоохранения и социальной защиты населения Республики Таджикистан; Республика Таджикистан, 734026 Душанбе, ул.…”

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Erectile dysfunction in patients after kidney transplantation and nephrectomy in living donors: literature review

Кадыров

Odilov

Саъдуллоев

et al. 2023

Androl. genit. hir.

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Аnalysis of the world literature shows that sexual dysfunction is a common problem in patients with chronic renal failure and after kidney transplantation in both men and women, which requires proper attention of specialists. The etiology of sexual dysfunction remains multifactorial and is associated with the level of azotemia, comorbidities, age, anemia, hormonal disorders, autonomic neuropathy, vascular diseases, hyperparathyroidism, hyperprolactinemia, drug side effects, and psychosocial factors. Sexual dysfunctions have a serious impact on the quality of social and family life of patients. On the one hand, in most cases, there is an increase in life expectancy and an improvement in the quality of life of patients after kidney transplantation. Due to the normalization of hormonal disorders, it improves sexual health (libido), overall health and fertility. On the other hand, after kidney transplantation, the prevalence of sexual dysfunction still remains at 46 % in both men and women. After kidney transplantation, erectile function in many patients improves and some recover. However, not all authors note an improvement in sexual dysfunction after kidney transplantation and leave the problem open. Conservative therapy with oral forms of drugs is most advantageous compared to cavernous injections or surgical treatment, if it does not affect the function of the graft. Sexual disorders after kidney transplantation remain a multifactorial disorder, and methods of their correction, especially in young patients, remain an urgent problem and require further study.

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