Sexual dysfunction among adolescent and young adult cancer patients: diagnostic and therapeutic approach

Nesher, Sharon Peleg; Luria, Myron H.; Shachar, Eliya; Percik, Ruth; Shoshany, Ohad; Wolf, Ido

doi:10.1097/spc.0000000000000595

Cited by 4 publications

(3 citation statements)

References 64 publications

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“…As SD is present in young female cancer survivors, sexual function needs to be addressed at the time of fertility preservation counseling and during follow-up visits. Possible approaches especially in adolescent and young cancer survivors are displayed in the review by Peleg Nesher et al [ 35 ]: after evaluation of SD in four steps as provided by Bartlik et al [ 36 ], patients can be offered couple/sex therapy, sexual medicine or further referral to a specialist (gynecologist/endocrinologist/urologist). Depending on current family planning, both contraception and hormone therapy as well as non-hormonal treatment options can be offered to improve vaginal dryness and other treatment-related discomfort.…”

Section: Discussionmentioning

confidence: 99%

Female cancer survivors: sexual function, psychological distress, and remaining fertility

Reiser,

Böttcher,

Ossig

et al. 2024

J Assist Reprod Genet

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Purpose Improved survivorship in cancer patients leads to new challenging issues including potential impairment of quality of life, sexual function, and fertility. The aim of this study was to assess sexual dysfunction (SD) and psychological distress in female cancer survivors who underwent fertility preservation in the past in comparison to reviewed healthy control data from other published studies. Additionally, our focus was on the difference in SD between women with current desire to get pregnant and already completed family planning. Methods In this prospective study, 53 female cancer survivors who underwent fertility preservation at time of cancer diagnosis between 2010 and 2020 were invited to a gynecological exam, laboratory assessment, and two questionnaires (Female Sexual Function Index (FSFI) and Hospital anxiety and depression scale (HADS)) in 2022. These scores were compared to results in the literature of healthy controls and depending on anti-Mullerian-hormone (AMH) levels, current desire to have a child, and age. Results After a mean follow-up time of 70 ± 50 months, SD was detected in 60.4% (n = 32) of the 53 included patients. Normal results regarding HADS-D/anxiety and HADS-D/depression were found in 88.7% and 94.3% of patients, respectively. At time of follow-up, 69.9% (n = 40) regained regular menstrual cycles, 52.6% (n = 20) < 40 years showed a diminished ovarian reserve with AMH levels < 1.1 ng/ml and 28.3% (n = 15) suffered from infertility. Conclusion Female cancer survivors may be at risk for SD. Cancer patients should be informed about possible sexual dysfunction already at the start of cancer treatment and during follow-up. In addition, contraception needs to be addressed if regular cycles occur as more than two-thirds of the women regained regular menstrual cycles.

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Section: Discussionmentioning

confidence: 99%

Female cancer survivors: sexual function, psychological distress, and remaining fertility

Reiser,

Böttcher,

Ossig

et al. 2024

J Assist Reprod Genet

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“…Poor sexual functioning and low sexual satisfaction are risk factors associated with a diminished quality of life 18 . Notably, sexual dysfunction is widely acknowledged as one of the most prevalent long-term effects of cancer treatments 17 , 19 , 20 .…”

Section: Introductionmentioning

confidence: 99%

Factors associated with sexual dysfunction in patients with colorectal cancer in Iran: a cross-sectional study

Dahouri,

Sahebihagh,

Gilani

2024

Sci Rep

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Sexual dysfunction is a prevalent issue among individuals diagnosed with colorectal cancer (CRC), significantly impacting their quality of life. However, limited research has explored the factors associated with sexual dysfunction in CRC patients in Iran. This cross-sectional study aimed to identify the demographic factors that may contribute to sexual dysfunction in this population. A cross-sectional study involving CRC patients was conducted from April 1, 2022, to May 1, 2022, in Tabriz, Iran. Ethical approvals were obtained, and convenience sampling was employed at outpatient chemotherapy centers in five Tabriz hospitals. Validated questionnaires, including participants characteristics form, the Female Sexual Function Index (FSFI) for females and International Index of Erectile Function (IIEF) for males, were utilized. Data were analyzed using IBM SPSS Statistics version 24, employing descriptive statistics and stepwise linear regression to assess association between mentioned factors and sexual function. Among 256 participants, 50.4% were males, 49.6% were females, and 80.5% were married. The predominant age range was 50–60 years. The study findings revealed a high prevalence of sexual dysfunction among both female (Mean ± SD: 10.91 ± 8.67, Min–Max: 3.20–33.00) and male (Mean ± SD: 27.64 ± 16.28, Min–Max: 11–62) CRC patients. Factors such as the presence of a colostomy for FSFI (P < 0.001), type of treatment received for both FSFI and IIEF (P < 0.001), type of housing for both FSFI and IIEF (P < 0.001), occupation for FSFI (P < 0.001), presence of other diseases for FSFI (P = 0.047), and time since the last chemotherapy session for FSFI (P = 0.018), Education for IIEF (P = 0.026), and Age for IIEF (P = 0.002) were identified as significant factors of sexual dysfunction. These demographic factors demonstrated varying effects on sexual function, underscoring the complexity of this issue. The results underscore the significance of addressing sexual health concerns in CRC patients and highlight the necessity for tailored interventions to enhance their overall well-being. Healthcare providers should recognize the influence of demographic factors on sexual function and contemplate integrating sexual health assessments and interventions into the care of CRC patients. Further research is needed to comprehend better the underlying mechanisms and devise effective strategies for managing sexual dysfunction in this population.

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“…This can be explained by the age-specific developmental tasks of AYAs, such as forming a partnership and family, establishing professional lives, and achieving financial independence (Zebrack and Isaacson, 2012). AYA cancer patients' biological and clinical conditions are also different from those of older patients (Peleg Nesher et al, 2022). AYA women with breast cancer showed a higher likelihood for developing clinical depression, higher levels of distress, and lower levels of QoL when compared with older breast cancer patients (Harrison et al, 2010;Champion et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

Sexuality, fertility, family planning, family life, and partnership in young breast cancer patients: a longitudinal study

et al. 2023

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ObjectivesAdolescent and young adult (AYA) breast cancer patients are often faced with sexuality-related problems. Since healthcare providers are often unfamiliar with problems specific to AYA cancer this topic is too little integrated into routine oncological care. The objective of this study was to analyze sexuality, fertility, family planning, family life, and partnership regarding satisfaction and supportive care needs in AYA breast cancer patients.MethodsA total of 139 AYA breast cancer patients were examined twice, 1 year apart. The patients were asked to complete several questionnaires and to answer multiple questions about satisfaction with sexuality, fertility, family planning, family life, and corresponding supportive care needs in these domains.ResultsWhile the patients were largely satisfied with their family life and partnerships, they were less satisfied with their sexuality and family planning. Only small mean score changes were observed in these variables over the course of a year. Being a parent already and having the possibility of further completing family planning were strongly associated with higher satisfaction and lower supportive care needs in these domains. Satisfaction was generally negatively associated with supportive care needs. Older age was predictive of lower satisfaction with sexuality at follow-up.ConclusionAYA cancer patients deserve special consultations concerning the impact of cancer and treatment on their sexuality and fertility, and it is especially important that women who have yet to complete their family planning be actively offered information and support concerning sexuality and fertility protection before beginning treatment.

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Sexual dysfunction among adolescent and young adult cancer patients: diagnostic and therapeutic approach

Cited by 4 publications

References 64 publications

Female cancer survivors: sexual function, psychological distress, and remaining fertility

Female cancer survivors: sexual function, psychological distress, and remaining fertility

Factors associated with sexual dysfunction in patients with colorectal cancer in Iran: a cross-sectional study

Sexuality, fertility, family planning, family life, and partnership in young breast cancer patients: a longitudinal study

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