Sexual and gonadal dysfunction in chronic kidney disease: Pathophysiology

Rathi, Manish; Ramachandran, Raja

doi:10.4103/2230-8210.93738

Cited by 69 publications

(71 citation statements)

References 45 publications

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“…Abnormalities anywhere along the neurovascular pathway can result in ED -the hypothalamic-pituitary-gonadal axis, vascular supply, and penile tissue damage from either infections or trauma. 13 Psychological factors such as fatigue, stress, and depression may result from chronic illness and contribute further to the development of ED.…”

Section: Male Sexual Dysfunction In Ckdmentioning

confidence: 99%

Endocrine Complications of Chronic Kidney Disease

Singh

Raed

Kari

2015

Chronic Renal Disease

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Section: Male Sexual Dysfunction In Ckdmentioning

confidence: 99%

Endocrine Complications of Chronic Kidney Disease

Singh

Raed

Kari

2015

Chronic Renal Disease

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“…The reason for infertility is due to disturbed pulsatile secretion of GnRH, which may be associated with high follicle-stimulating hormone (FSH), luteinizing hormone (LH) and prolactin levels [1]. These hormonal disturbances can reverse after transplant, resulting in normal ovulatory cycles and regular menstruation [4,5]. However, female patients with chronic kidney disease may develop early menopause, 4.5 years earlier than general population [6].…”

Section: Discussionmentioning

confidence: 99%

An Overview on Fertility Outcome in Renal Transplant Recipients

Mishra

Nanda

Mistry

et al. 2016

J Obstet Gynecol India

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Background The number of patients undergoing renal transplant are increasing with time. Most of these patients fall in the reproductive age group, who are going to conceive sooner or later. But there are few recipients who either are infertile before transplant or became infertile due to underlying renal pathology responsible for transplantation. Objective To study fertility outcome in female renal transplant recipients. Materials and Methods Study design: This is a retrospective study conducted at tertiary health center in Ahmedabad, from 2004 to 2014. Inclusion criteria: Renal transplant recipients in the reproductive age group (20-40 years of age) were followed up in gynecology outdoor patient department. Sample size: There were 211 female renal transplant recipients, out of which 113 (53.5 %) patients had complete family, 3 (1.41 %) patients were infertile, 16 (7.58 %) patients have conceived, 33 (15.63 %) patients were lost to follow-up and remaining 46 (21.8 %) did not try for pregnancy. Exclusion criteria: Unmarried patients, divorced and widow patients were excluded. Results Out of 19 patients, 16 patients conceived and 3 were infertile. The main cause of infertility in these patients was ovarian factor in 2 patients and tubal factor in 1 patient. Among 16 patients, 8 patients had missed abortion, 2 patients had preterm deliveries and 6 patients had term deliveries. Conclusion Peritransplant and preconceptional counseling plays an important role for renal transplant recipients to help them understand the effect of renal pathology and transplantation on their fertility. They can have good fertility and pregnancy outcome with optimum functioning graft.

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“…Mejía-Rodríguez et al found that bromocriptine treatment in patients with left-ventricular hypertrophy and end-stage renal disease on peritoneal dialysis decreased left-ventricular mass [97]. Symptomatic hyperprolactinemia in patients with chronic kidney disease can be treated with DA [98]. In currently available literature no clear recommendations regarding treatment of hyperprolactinemia in liver diseases exists.…”

Section: Management Of Other Causes Of Hyperprolactinemiamentioning

confidence: 99%

Untitled

2015

Endocr oncol metab

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Objectives: Hyperprolactinemia is a common endocrine problem seen in everyday practice. Therefore, the Croatian society for endocrine oncology decided to write Croatian guidelines for the management of hyperprolactinemia that implements current scientific evidence with acknowledgement of economic and cultural specificities in Croatia. Methods: These guidelines were written by a Working group in the Croatian society for endocrine oncology, which included experts from different medical specialities that manage hyperprolactinemia, and were based on relevant scientific data. Results: These guidelines provide a comprehensive review of prolactin pathophysiology, the aetiology of hyperprolactinemia, as well as recommendations for the diagnostic and therapeutic approach to patients with hyperprolactinemia. Conclusion: These practical guidelines are in agreement with current scientific knowledge and will ensure better management of hyperprolactinemia in Croatia.

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Sexual and gonadal dysfunction in chronic kidney disease: Pathophysiology

Cited by 69 publications

References 45 publications

Endocrine Complications of Chronic Kidney Disease

Endocrine Complications of Chronic Kidney Disease

An Overview on Fertility Outcome in Renal Transplant Recipients

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