Sex steroid and tropic hormone levels may be associated with postoperative prognosis of vitrectomy in Korean postmenopausal women

Abstract

Sex steroid and tropic hormones may be associated with postoperative ophthalmologic outcomes in the postmenopausal women undergoing vitrectomy. Further larger scale studies will be necessary to confirm these preliminary results.

Homocysteine as a Risk Factor for Hypertension: A 2-Year Follow-Up Study

“…Firstly, the 2-year follow-up period might be insufficient, and could lead to bias in underestimating the influence of Hcy on the disease. However, as mentioned above, a similar approximately U-shaped curve for risk was found in a 17.5-year follow-up study [33] , and more research or meta-analyses are needed to assess any potential bias. From 2010 to the present, we measured only two blood biochemical parameters.…”

Sex hormone levels and risk of primary open-angle glaucoma in postmenopausal women

“…The association between higher testosterone and higher IOP is consistent with three previous small studies. 27, 28 Yu et al 27 observed among 23 postmenopausal women not on PMH that testosterone was significantly correlated with higher IOP (r=0.38). Similarly, Toker et al 28 observed among both menopausal women on PMH (n=30) and menopausal women who never used PMH (n=32) that higher testosterone levels were significantly correlated with higher IOP (r = 0.48 in women on PMH and r=0.42 in women not on PMH) and Karaca Adiyeke et al 29 reported that among 50 women with polycystic ovarian syndrome, higher testosterone was correlated with higher IOP (r=0.34).…”

“…While a few studies have evaluated the relation between major circulating sex hormones and IOP, 27–29 the data is scarce for the relation between sex hormones and glaucoma. 30 Given the associations with POAG of PMH use, 6, 7 early menopause / bilateral oophorectomy, 6, 12, 13 and higher BMI, 23–25, 31 which also influence circulating hormone levels in postmenopausal women, 32–34 we hypothesized that endogenous circulating sex hormone levels may be associated with POAG risk.…”

Cross Sectional Study among Intraocular Pressure, Mean Arterial Blood Pressure, and Serum Testosterone according to the Anthropometric Obesity Indices in Korean Men

“…Testosterone reduces activity of eNOS in the trabecular meshwork to lower the outflow capacity to increase IOP [ 9 23 ]. In animal study conducted on both male and female rats, DHTS decreases NOS activity, NOS mRNA expression, and the number of NOS+ neurons in the central nervous system.…”