Sex‐Specific Associations of Risk‐Based Alcohol Drinking Level with Cardiovascular Risk Factors and the 10‐Year Cardiovascular Disease Risk Scores

Lee, Kayoung

doi:10.1111/acer.13798

Cited by 2 publications

(2 citation statements)

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“… 6 A similar recent study in South Korea revealed less significant associations of drinking levels with cardiovascular risk factors in women than in men. 7 In contrast, a register-based cohort study in Denmark reported comparable higher risks of a wide range of somatic diseases in those with alcohol-dependency in both genders. 2 …”

Section: Introductionmentioning

confidence: 92%

Effects of age and gender on the relationship between alcohol use disorder and somatic diseases: a national register study in Norway

2021

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ObjectiveThis study aimed to examine how age and gender moderate the associations between alcohol use disorders (AUD) and several somatic diseases.Design and settingWe performed a retrospective, register-based cohort study with 6-year follow-up of patients with AUD and the general population. Data were acquired from the Norwegian Patient Registry. Cox regressions were used to estimate HRs of somatic diseases.ParticipantsPatients with AUD (17 023; 0.4%) were compared with the population without AUD (4 271 559; 99.6%), with adults aged 18 years or older who were registered residents of Norway on 1 January 2008.Main outcomesDichotomous variables of 12 specific somatic diseases (cardiovascular diseases, endocrine, nutritional, and metabolic diseases, cancer, and infectious diseases) were assessed. Diagnoses were set in specialist healthcare services.ResultsPatients with AUD, compared with a population without AUD, experienced a significantly greater burden of all studied somatic diseases. Middle-aged adults with AUD had increased risks (p<0.05) for hypertension; ischaemic diseases; pulmonary diseases; cerebrovascular diseases; malnutrition; metabolic disorders; cancer; and influenza and pneumonia than younger and older adults with AUD. For most somatic diseases, we found no differences between younger versus older adults with AUD, and between females versus males with AUD (p>0.05). Males with AUD had significantly higher risks for pulmonary heart diseases (HR=3.9, 95% CI 3.3 to 4.6) and metabolic disorders (HR 4.7, 95% CI 4.5 to 5.0), while females with AUD had a significantly higher risk for viral hepatitis (HR=4.4, 95% CI 3.8 to 5.1).ConclusionsAge moderated the associations between AUD and most somatic diseases, with middle-aged adults with AUD having a greater increased risk of somatic diseases compared with younger and older adults with AUD. Gender only moderated associations between AUD and pulmonary heart diseases, metabolic disorders and viral hepatitis. This has implications for the prioritisation of somatic resources among patients with AUD.

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Section: Introductionmentioning

confidence: 92%

Effects of age and gender on the relationship between alcohol use disorder and somatic diseases: a national register study in Norway

2021

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“…Существуют пол-специфические эффекты алкоголя на липидный профиль, полученные на примере корейской популяции [17], которые, возможно, могут обусловливать разные пути формирования алкогольиндуцированного сердечно-сосудистого континуума. При этом, увеличение потребления алкоголя положительно ассоциируется со смертностью от всех причин у обоих полов [18].…”

Section: традиционные факторы ссрunclassified

Gender differences of cardiovascular risk

2019

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Despite the many unresolved issues on gender characteristics of cardiovascular health, accumulated data allows to generalize global, national, ethnic, and social patterns. There are small deal of domestic studies that not always presented at a high evidentiary level. Meanwhile, in foreign literature, the study of gender characteristics is given an important place. The purpose of this review is to highlight the gender characteristics of the prevalence of the main cardiovascular risk factors according to literature data. The article shows the gender trends in the prevalence of the main determinants of cardiovascular health. It can be assumed that the cardiovascular continuum has a gender orientation and is triggered by men and women with “its own” cardiovascular risk factors. The development of this direction will help to form a gender-based prevention and treatment strategy to predict and limit adverse outcomes in a particular region of the country.

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Sex‐Specific Associations of Risk‐Based Alcohol Drinking Level with Cardiovascular Risk Factors and the 10‐Year Cardiovascular Disease Risk Scores

Abstract: Risk-based drinking levels were more likely to have dose-dependent associations with CV risk factors in men than in women and had inverse relationships with 10-year CVD risk in both men and women.

Cited by 2 publications

References 32 publications

Effects of age and gender on the relationship between alcohol use disorder and somatic diseases: a national register study in Norway

Effects of age and gender on the relationship between alcohol use disorder and somatic diseases: a national register study in Norway

Gender differences of cardiovascular risk

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