To analyze if the spread of HIV is related to economic inequality we estimate multilevel models of the individual probability of HIV infection among young Malawian women. We find a positive association between HIV infection and inequality at both the neighborhood and district levels, but no effect of individual poverty. We also find that the HIV-inequality relationship is related to risky sex, gender violence, and return migration, though no variable completely replaces economic inequality as a predictor of HIV infections. The HIV-inequality relationship does not seem to be related to bad health, gender gaps in education or women's market work.JEL: I12.