Abstract:Background
Sex and age have substantial influence on thyroid function. Sex influences the risk and clinical expression of thyroid disorders (TDs), with age a proposed trigger for the development of TDs. Cardiac function is affected by thyroid hormone levels with gender differences. Accordingly, we investigated the proteomic changes involved in sex based cardiac responses to thyroid dysfunction in elderly mice.
Methods
Aged (18–20 months) male and female C57BL/6 mice were fed diets to create euthyroid, hypoth… Show more
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