2020
DOI: 10.1186/s12953-020-00167-3
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Sex impacts cardiac function and the proteome response to thyroid hormone in aged mice

Abstract: Background Sex and age have substantial influence on thyroid function. Sex influences the risk and clinical expression of thyroid disorders (TDs), with age a proposed trigger for the development of TDs. Cardiac function is affected by thyroid hormone levels with gender differences. Accordingly, we investigated the proteomic changes involved in sex based cardiac responses to thyroid dysfunction in elderly mice. Methods Aged (18–20 months) male and f… Show more

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Cited by 3 publications
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