Sex divergent behavioral responses in platform-mediated avoidance and glucocorticoid receptor blockade
Carly J. Halcomb,
Trey R. Philipp,
Parker S. Dhillon
et al.
Abstract:Women are more likely than men to develop anxiety or stress-related disorders. A core behavioral symptom of all anxiety disorders is avoidance of fear or anxiety eliciting cues. Recent rodent models of avoidance show reliable reproduction of this behavioral phenomenon in response to learned aversive associations. Here, a modified version of platform-mediated avoidance that lacked an appetitive task was utilized to investigate the learning and extinction of avoidance in male and female C57BL6/J mice. Here, we f… Show more
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