Sex Disparity in Food Allergy: Evidence from the PubMed Database

Kelly, Caleb; Gangur, Venu

doi:10.1155/2009/159845

Cited by 63 publications

(65 citation statements)

References 38 publications

(44 reference statements)

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“…In recent studies, in agreement with our results, male gender [26], infantile eczema [27] and a family history of atopy [28,29] have been determined as important risk factors for the development of FA. Moreover, many studies have shown an association with AD.…”

Section: Discussionsupporting

confidence: 91%

Clinical Features of Food Allergy during the 1st Year of Life: The ADAPAR Birth Cohort Study

Doğruel

Bingöl

Altıntaş

et al. 2016

Int Arch Allergy Immunol

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Background: Although food allergies (FAs) occur most commonly during the 1st year of life, there is limited information available regarding the epidemiology of FAs. In this study, we investigated the incidence of FA and the associated risk factors during the 1st year of life in southeast Turkey. Methods: This study is a prospective evaluation of 1,377 infants born at the Balcalı Hospital (Çukurova University) and includes four routine follow-up assessments until the age of 1 year. At birth, a physical examination was performed, cord blood samples were taken, and parents completed a baseline questionnaire. Follow-up visits were scheduled at 3, 6 and 12 months and included the infants' physical examination and a follow-up questionnaire. A skin prick test (SPT) was performed and food-specific IgE levels were measured at 6 and 12 months. Telephone interviews were conducted when the infants were 9 months of age, and the questionnaire was administered. The diagnosis of FA was based on food-specific IgE levels, positive SPT results, associated clinical findings and an oral food challenge (OFC) test. Results: Patient histories, physical examinations and laboratory results indicated a possible FA in 90 infants (6.5%) during the 1st year of life. All of them underwent OFC testing with the suspected foods, and FA was confirmed in 33 cases (2.4%). Cow's milk allergy was the major cause of FA. Skin reactions were major clinical findings in FA. A family history of atopy was identified as the major risk factor for FA. Conclusions: The prevalence and risk factors of FA in our region are consistent with those reported in the literature.

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Section: Discussionsupporting

confidence: 91%

Clinical Features of Food Allergy during the 1st Year of Life: The ADAPAR Birth Cohort Study

Doğruel

Bingöl

Altıntaş

et al. 2016

Int Arch Allergy Immunol

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“…Rather, male gender, eczema, other food allergies, and asthma were more frequently seen in association with positive WIgE, partly confirming previous results [2, 33]. …”

Section: Discussionsupporting

confidence: 88%

Identifying True Celiac Disease and Wheat Allergy in the Era of Fashion Driven Gluten-Free Diets

Spoerl

Bastid²,

Ramadan

et al. 2019

Int Arch Allergy Immunol

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Background: Diagnosing both celiac disease (CD) and wheat allergy (WA) might be challenging due to the increasingly popular gluten-free diets. Objectives: This study investigates the value of anti-tissue transglutaminase IgA (tTGIgA) and wheat-specific IgE (WIgE), and identifies clinical and serological features associated with CD and WA. Method: Serological markers of autoimmunity and allergy along with medical charts of patients assessed for tTGIgA and WIgE between 2010 and 2016 were evaluated. Results: During the last years, an increasing number of patients have been tested for tTGIgA, while the number of positive results decreased linearly. Among the 2,965 patients included, 128 patients showed at least once a positive tTGIgA. All patients with tTGIgA levels higher than the 12-fold upper normal limit had CD. The ratio of tTGIgA/total IgA did not perform better as a diagnostic test for CD compared to tTGIgA. tTGIgA and anti-nuclear antibodies were significantly associated. WA was only rarely investigated, particularly in adults. However, positive WIgE were found in nearly 50% of the cases. WIgE and tTGIgA values were negatively correlated. Conclusions: tTGIgA were increasingly tested, while the rate of positive results decreased in recent years, possibly reflecting the impact of current alimentary trends on clinical practice. Associated autoimmune disease was frequently found in CD. High levels of tTGIgA accurately predicted CD diagnosis. WA was rarely investigated and deserves more attention, in particular in children with atopic background. WA does not seem to be associated with CD.

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“…De los pacientes, la mayoría fue del sexo masculino (56.7 %), tendencia que persistió en el resto de las patologías alérgicas y concuerda con los datos evidenciados en la mayoría de la literatura internacional. 5,6,7,8,9,10,11,12 En un estudio regional previo no se identifi có diferencia en la prevalencia de rinitis y asma en la población preescolar entre hombres y mujeres. 4 Un aspecto importante es el análisis de los regí-menes de aseguramiento.…”

Section: Discussionunclassified

Caracterización de los niños menores de cinco años con sospecha de enfermedades alérgicas

Vásquez

Olaya

Cleves

et al. 2018

RAM

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Antecedentes: Los síntomas de enfermedad alérgica constituyen una causa frecuente de consulta en la infancia.Objetivo: Describir el perfil de una población de preescolares colombianos atendidos en un servicio de alergología y evaluar los posibles factores de riesgo.Métodos: Estudio descriptivo trasversal de pacientes menores de cinco años evaluados durante un año. Se realizó historia clínica completa y estudio alergológico con pruebas cutáneas según el caso. Se analizaron factores de riesgo mediante análisis multivariado.Resultados: Se incluyeron 674 pacientes, 382 (52.7 %) hombres. La mediana de edad fue 34 meses. Los motivos de consulta fueron tos o sibilancias recurrentes (54.3 %), rinitis (48.7 %) y eccema (32.2 %). Se realizaron pruebas cutáneas con aeroalérgenos a 299 pacientes (48 %) y con alimentos a 170 (27 %), encontrando positividad en 114 (38 %) y 16 (9.4 %), respectivamente. Los principales sensibilizadores fueron los ácaros y el huevo. Se encontró asociación directa entre eccema y prematurez (OR = 0.496; IC 95 % = 0.289-0.823), tos/sibilancias recurrentes e historia familiar de alergia (OR = 1.837; IC 95 % = 1.306-2.586), y tos/sibilancias recurrentes y antecedente de bronquiolitis (OR = 2.646; IC 95 % = 1.812-3.886).Conclusión: Los síntomas respiratorios representaron la principal causa de consulta. Los ácaros fueron los alérgenos más identificados. La historia familiar de alergia y la bronquiolitis parecen ser factores de riesgo.

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Sex Disparity in Food Allergy: Evidence from the PubMed Database

Cited by 63 publications

References 38 publications

Clinical Features of Food Allergy during the 1st Year of Life: The ADAPAR Birth Cohort Study

Clinical Features of Food Allergy during the 1st Year of Life: The ADAPAR Birth Cohort Study

Identifying True Celiac Disease and Wheat Allergy in the Era of Fashion Driven Gluten-Free Diets

Caracterización de los niños menores de cinco años con sospecha de enfermedades alérgicas

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