Sex dimorphism and tissue specificity of gene expression changes in aging mice
Dantong Zhu,
Matt Arnold,
Brady Samuelson
et al.
Abstract:Background
Aging is a complex process that involves all tissues in an organism and shows sex dimorphism. While transcriptional changes in aging have been well characterized, the majority of studies have focused on a single sex and sex differences in gene expression in aging are poorly understood. In this study, we explore sex dimorphism in gene expression in aging mice across three tissues.
Methods
We collected gastrocnemius muscle, liver and white adipose tissue from young (6 months, n = 14) and old (24 mon… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.