Sex differences on outcomes of catheter ablation of ventricular tachycardia in patients with structural heart disease: A real-world systematic review and meta-analysis

Prasitlumkum, Narut; Navaravong, Leenhapong; Desai, Aditya; Chewcharat, Pol; Gandhi, Haresh; Perswani, Prinka; Vallabhajosyula, Saraschandra; Cheungpasitporn, Wisit; Akoum, Nazem; Jongnarangsin, Krit; Chokesuwattanaskul, Ronpichai

doi:10.1016/j.hroo.2022.09.009

Cited by 3 publications

(2 citation statements)

References 55 publications

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“…Recent registries suggested the underrepresentation of women, yet insignificant differences in mortality, recurrence rates, or even lower AICD shock were observed. [3][4][5] In real-world observations, a similar limitation, the paucity of data in female cohorts, 6,7 bar the translation of such data into meaningful clinical insights. Only a handful of trials explored sex differences in VT outcomes, failing to better characterize the current circumstances.…”

Section: Introductionmentioning

confidence: 99%

Sex differences in clinical characteristics, management, and outcomes in patients admitted for ventricular tachycardia: 2016–2018

Prasitlumkum

Chokesuwattanaskul

Kaewput

et al. 2023

Cardiovasc electrophysiol

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IntroductionThe concurrent data on sex disparities in VT management and outcomes have remained unclear. Therefore, our objective was to determine the impact of sex on ventricular tachycardia (VT) management and outcomes in patients admitted with VT, dervied from the US National Inpatient Sample database (NIS).MethodsWe used data from the US NIS to identify hospitalized adult patients who were admitted with VT between 2016 and 2018. Regression analysis was conducted to evaluate the impact of sex on VT management, in‐hospital mortality, complications, length of stay, and hospitalization costs.ResultsOf the database, a total of 146 070 patients, who were primarily hospitalized for VT, were approximated. Among these, women comprised 25.5%; they were significantly younger and had fewer comorbidities. Of procedural aspects, women were less likely to receive an angiogram, mechanical support, implantable cardioverter‐defibrillator implantation, and VT ablation compared to men. Notably, women were associated with higher do‐not‐resuscitate rates and in‐hospital cardiac arrests than men. No differences in in‐hospital mortality and cardiogenic shock were observed between men and women (p > .05). Length of stay was significantly longer for women, while no differences in hospital costs were observed in both sexes.ConclusionSignificant sex disparities in management and outcomes were observed in admitted patients with VT. Our results reflect the need for further studies to explore factors causing such diversities.

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Section: Introductionmentioning

confidence: 99%

Sex differences in clinical characteristics, management, and outcomes in patients admitted for ventricular tachycardia: 2016–2018

Prasitlumkum

Chokesuwattanaskul

Kaewput

et al. 2023

Cardiovasc electrophysiol

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“…Similar to the African American population, the study reveals relatively low prevalence of AF in the population from sub-Saharan Africa. In a meta-analysis of observational studies, Prasitlumkum et al 21 have evaluated sex-specific differences in the outcomes after ventricular tachycardia (VT) ablation for structural heart disease. They found increasing representation of women in more recent studies and no difference in mortality or rehospitalization for VT among men and women.…”

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confidence: 99%

Special issue on electrophysiology and arrhythmia management around the globe: Challenges and opportunities explored

Srivatsa

2022

Heart Rhythm O2

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Is Investigator Sex Associated With Female Underenrollment in Arrhythmia Trials?

Quraishi,

Sapp,

Van Spall

et al. 2024

JACC: Clinical Electrophysiology

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Sex differences on outcomes of catheter ablation of ventricular tachycardia in patients with structural heart disease: A real-world systematic review and meta-analysis

Cited by 3 publications

References 55 publications

Sex differences in clinical characteristics, management, and outcomes in patients admitted for ventricular tachycardia: 2016–2018

Sex differences in clinical characteristics, management, and outcomes in patients admitted for ventricular tachycardia: 2016–2018

Special issue on electrophysiology and arrhythmia management around the globe: Challenges and opportunities explored

Is Investigator Sex Associated With Female Underenrollment in Arrhythmia Trials?

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