Sex differences need to be considered when treating women with psychotropic drugs

Sommer, Iris E.; Brand, Bodyl A.; Stuijt, Clementine C.M.; Touw, Daan J.

doi:10.1002/wps.21155

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2024

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Cited by 2 publications

References 9 publications

(22 reference statements)

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What Do Four Decades of Research Tell Us About the Association between Childhood Adversity and Psychosis: An Updated and Extended Multi-Level Meta-Analysis

Zhou,

Sommer,

Yang

et al. 2024

Preprint

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What Do Four Decades of Research Tell Us About the Association between Childhood Adversity and Psychosis: An Updated and Extended Multi-Level Meta-Analysis

Zhou,

Sommer,

Yang

et al. 2024

Preprint

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Factors Associated with Anxiety, Depression, and Quality of Life in Patients with Psoriasis: A Cross-Sectional Study

Cipolla,

Catapano,

Bonamico

et al. 2024

Brain Sciences

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Background: Psoriasis is a chronic skin disorder affecting 2–3% of the global population, and is associated with several comorbidities, including psychiatric disorders. This study aimed to identify factors influencing anxiety, depression, and quality of life (QoL) in patients with psoriasis. Methods: This observational study included 112 patients diagnosed with psoriasis. Dermatological and psychiatric assessments were conducted using Psodisk, the Hamilton Anxiety Rating Scale (HAM-A), Hamilton Depression Rating Scale (HAM-D), Symptom Checklist-90-Revised (SCL-90-R), and 36-Item Short Form Health Survey (SF-36). Descriptive statistics, correlation analyses, and multivariate regression models were employed. Results: The sample was predominantly middle-aged males (mean age 48.91 years). Females (p < 0.001), patients with arthritis (p < 0.05), and those with a sedentary lifestyle (p < 0.05) showed higher anxiety and depression scores. Psodisk subscales significantly correlated with psychiatric symptoms and QoL measures (p < 0.001). Pain (B: 0.63, p < 0.05; B: −2.03, p < 0.01) and sleep disturbances (B: 0.68, p < 0.01; B: 0.60, p < 0.01; B: −1.46, p < 0.01; B: −1.57, p < 0.05; B: 3.91, p < 0.05) emerged as major predictors of poor mental health and reduced QoL. Conclusions. The study underscores the complex relationship between psoriasis, psychiatric comorbidities, and QoL. Key factors exacerbating anxiety and depression include female gender, arthritis, and sedentary lifestyle. Comprehensive management of psoriasis should address both dermatological and psychological aspects, with a focus on pain relief and improving sleep quality to enhance overall patient well-being.

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Sex differences need to be considered when treating women with psychotropic drugs

Cited by 2 publications

References 9 publications

What Do Four Decades of Research Tell Us About the Association between Childhood Adversity and Psychosis: An Updated and Extended Multi-Level Meta-Analysis

What Do Four Decades of Research Tell Us About the Association between Childhood Adversity and Psychosis: An Updated and Extended Multi-Level Meta-Analysis

Factors Associated with Anxiety, Depression, and Quality of Life in Patients with Psoriasis: A Cross-Sectional Study

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