Background:The purpose of this study was to use SEM to investigate the relationship between a latent construct of metabolic syndrome (MetS) and health-related quality of life (HRQOL) through a measure of social risk (SR) in younger adults.Methods: Data for this research came from the 2013-14 NHANES and included (N=1,060) adults 20 to 49 years of age. A latent construct of MetS was created using five indicators that included waist circumference, high density lipoprotein, triglycerides, glucose, and mean arterial pressure. A SR score was created using four variables that included race (non-white), income (below poverty threshold), education (less than high school), and marital status (single). HRQOL was determined from a single five category question regarding self-rated general health ranging from excellent to poor.
Results:The MetS measurement model showed adequate fit (χ 2 /df = 4.76, GFI = 0.99, CFI = 0.99, and RMSEA = 0.06) with all indicators significantly (ps<.001) loading to the construct. Multi-group analysis indicated a significant lack of measurement invariance by sex (χ 2 = 1.99, p=.017). Sex-specific structural models showed adequate fit with significant direct effects (beta, p-value) of MetS on HRQOL (males: -0.45, <.001 and females: -0.51, <.001) and SR on HRQOL (males: -0.16, <.001 and females: -0.15, <.001). SR partially mediated the MetS and HRQOL relationship with a positive indirect effect seen in males (b=.002, p=.020) and a negative indirect effect seen in females (b=-.002, p=.004).
Conclusion:SR was found to mediate the MetS and HRQOL relationship in younger adults, with SR contributing to its total negative relationship in females.