Sex differences in psychotic and non-psychotic major depressive disorder in a Chinese Han population

Ling, Qi; Zhang, Yaping; Wang, Liewei; Wang, Ruoxi; Wu, Jiang; Zhou, Xin; Chen, Jing; Zhang, Shufang; Zhou, Yongjie; Zhang, Xiang Yang

doi:10.1016/j.jad.2020.03.003

Cited by 12 publications

(7 citation statements)

References 52 publications

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“…In line with previously extensive epidemiological studies support that female were at higher risk of depression ( Kessler et al., 2003 ; Lim et al., 2018 ), the present study revealed that female non-medical workers on the front-line had a higher rate of clinically significant depression compared to males. Sex difference has been widely recognized for the occurring of depression, and a range of biopsychosocial factors may contribute to this gender difference in depression ( Qi et al., 2020 ). Hence, special attention should be paid to mental health of female volunteers during epidemic outbreaks.…”

Section: Discussionmentioning

confidence: 99%

Depressive symptoms in the front-line non-medical workers during the COVID-19 outbreak in Wuhan

Fang

Zhang

Teng

et al. 2020

Journal of Affective Disorders

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Highlights This is the first study to understand the psychological impacts in the front-line non-medical workers during the COVID-19. The results showed that 50.3% front-line non-medical workers reported the clinically significant symptoms of depression. The post-90 s (the generation born after 1990s) and females showed increased risk for depression. Targeted psychological intervention should be developed to improve the mental health of non-medical workers.

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Section: Discussionmentioning

confidence: 99%

Depressive symptoms in the front-line non-medical workers during the COVID-19 outbreak in Wuhan

Fang

Zhang

Teng

et al. 2020

Journal of Affective Disorders

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“…However, this study enrolled participants from developed countries. Many previous studies inferred that there is a genderspecific association between MetS and MDD [16,17].…”

Section: Introductionmentioning

confidence: 99%

Metabolic syndrome associated with the onset of depressive symptoms among women but not men in rural Northeast China

Guo

et al. 2020

BMC Psychiatry

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Background: The present study aimed to assess the cumulative incidence of major depressive disorder (MDD) among rural Chinese residents. Furthermore, we intended to estimate whether metabolic syndrome (MetS) was associated with MDD by both cross-sectional and prospective analysis. Method: Data of 11,675 residents (46.3% men) was used for cross-sectional analysis. The residents were followed up with median 4.66 years. MDD was diagnosed using the Patient Health Questionnaire-9 (PHQ-9). The data of 2796 individuals without any depressive symptoms was used for prospective analysis. Result: With median of 4.66 years follow-up, the cumulative incidence of MDD among rural residents was 3.9%. Women had significantly higher cumulative incidence of MDD than men (5.3% for women and 2.9% for men, P < 0.01). The incidence of MDD was significantly higher among women with MetS (7.3% vs. 3.8%, P < 0.001), hypertriglyceridemia (7.0% vs. 4.5%, P < 0.001) or elevated blood pressure (6.4% vs. 3.4%, P < 0.001) at baseline compared with those without them. There was no incidence difference of MDD among men with or without baseline metabolic disorders. In prospective study, after adjusting possible confounders, baseline MetS was associated with higher incidence of MDD (OR: 1.82, 95%CI: 1.01, 3.27, P = 0.045) in women but not men (OR: 1.84, 95%CI: 0.88, 3.83, P = 0.104). Conclusion: Cumulative incidence of MDD in rural China was higher among women than among men. Baseline MetS was associated with higher cumulative incidence of MDD in women but not men. More concern should be put on women with MetS in case of onset depressive symptom in future.

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“…More specifically, both previous studies enrolled samples more vulnerable to depression (married people and students) than the sample (general population) in the present study [ 11 , 37 , 38 ]. In support of this view, some general population studies show no gender differences in depression [ 6 – 8 ].…”

Section: Discussionmentioning

confidence: 76%

“…Findings on gender differences in depression are inconsistent. Some studies indicate that women have a higher prevalence of depression than men [1][2][3][4][5], whereas others report no gender differences in depression [6][7][8]. There is also evidence that more men than women report depression in some situations [9,10].…”

Section: Introductionmentioning

confidence: 99%

Gender Differences in Depression in the General Population of Indonesia: Confounding Effects

Mumang

Syamsuddin

Maria

et al. 2021

Depression Research and Treatment

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Background. Research findings on gender differences in depression are inconsistent. This study investigated gender and depression in the Indonesian population and considered possible confounding effects. Methods. This was a cross-sectional study. Participants completed the following self-report measures: demographic characteristic questions, the Cultural Orientation Scale, and the Center for Epidemiological Studies Depression Scale. Gender differences in depression were examined using a generalized linear model. Results. After withdrawals, 265 men and 243 women remained. Women and men did not differ in overall scores and four-factor depression symptoms even after adjusting for cultural orientation and demographic confounding factors, except for the depression symptoms “crying,” “cannot get going,” and “people were unfriendly.” Gender differences in depression became significant after adjusting for stereotypical symptom variance. Men reported being lonelier than women. Conclusions. Possible confounding effects on the association between gender and depression are methodological issues, cultural orientation transition, and stereotypical symptoms. Low depression scores found for gender may reflect dimension-counterpart coping strategies.

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Sex differences in psychotic and non-psychotic major depressive disorder in a Chinese Han population

Cited by 12 publications

References 52 publications

Depressive symptoms in the front-line non-medical workers during the COVID-19 outbreak in Wuhan

Depressive symptoms in the front-line non-medical workers during the COVID-19 outbreak in Wuhan

Metabolic syndrome associated with the onset of depressive symptoms among women but not men in rural Northeast China

Gender Differences in Depression in the General Population of Indonesia: Confounding Effects

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