Sex differences in growth and mortality in pregnancy-associated hypertension
Jess C. Hercus,
Katherine X. Metcalfe,
Julian K. Christians
Abstract:Background
It is hypothesized that male fetuses prioritize growth, resulting in increased mortality, whereas females reduce growth in the presence of adversity. Preeclampsia reflects a chronic condition, in which fetuses have the opportunity to adjust growth. If females reduce their growth in response to preeclampsia, but males attempt to maintain growth at the cost of survival, we predict that differences in birthweight between preeclamptic and non-preeclamptic pregnancies will be greater among females, where… Show more
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