Sex Differences in Acute Coronary Syndrome: Insights From an Observation Study in Low socio-economic Cohort From India

Rangaiah, Sunil Kumar Kondethimmannahally; Kaur, Sumandeep; Sidhu, Navdeep Singh; D, Ramesh; Veerappa, Kumaraswamy; Manjunath, Cholenahally Nanjappa

doi:10.2217/fca-2020-0072

Cited by 2 publications

(1 citation statement)

References 22 publications

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“…Характер боли в груди у пациентов с ОКС в одних ситуациях имеет решающее диагностическое значение, но в других случаях указывает лишь направление, в котором должно вестись исследование. Известно, что у женщин ИБС развивается на 5-10 лет позже, чем у мужчин [3,5], т. е. в более старшем возрасте и с другой спецификой симптомов [6,7]. Кроме того, исследования показывают, что врачи применяют менее агрессивный диагностический и терапевтический подходы у женщин с ИБС, чем у мужчин [8].…”

Section: Cardiology кардиология введениеunclassified

Clinical symptoms and ECG data in women with acute coronary syndrome

Sumin

Vakhrushev

Щеглова

2023

Acta biomedica scientifica

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Background. There are many differences in chest pain symptoms between men and women in terms of location, nature, and additional symptoms. The issue of describing the differences in chest pain in men and women with acute coronary syndrome (ACS), as well as their correlation with changes in the electrocardiogram (ECG) and coronary angiography (CAG) remains relevant.Methods. The study included 588 patients of the cardiology department of the Novokuznetsk City Clinical Hospital No. 1 from 2013 to 2017 with a diagnosis of ACS. Depending on the gender, the subjects were divided into two groups: Group I – 330 men; Group II – 258 women.Results. ACS with ST elevation was more common in men (45.8 %) than in women (33.3 %; p = 0.002). There were no pathological ECG changes in women in 58.1 % of cases, in men – in 45.5 % (p < 0.001). ECG type Q/ST elevation was detected more often in men (45.8 %) than in women (33.3 %; p = 0.002). The absence of coronary artery lesions was observed in 27.9 % of men and 44.2 % of women (p < 0.001). Hemodynamically significant coronary artery stenosis was more common in men (57.6 %) than in women (38.7 %; p < 0.001). In a typical angina clinic, hemodynamically significant coronary artery disease in patients with Q/without ST elevation ACS was detected in 40.2 % of men and in 58.5 % of women (p = 0.002). In the atypical angina clinic, hemodynamically significant lesions of coronary artery were more common in men (40.6 %) than in women (34.1 %; p = 0.02).Conclusion. In women atypical chest pains and intact coronary arteries were detected more often than in men, and hemodynamically significant coronary artery stenosis were found less often than in men. In men, a more pronounced pathology of the coronary arteries in ACS was revealed, in women – great difficulties in diagnosing ACS.

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Section: Cardiology кардиология введениеunclassified

Clinical symptoms and ECG data in women with acute coronary syndrome

Sumin

Vakhrushev

Щеглова

2023

Acta biomedica scientifica

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Gender inequalities in secondary prevention of cardiovascular disease: a scoping review

López Ferreruela,

Obón Azuara,

Malo Fumanal

et al. 2024

Int J Equity Health

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Background Despite significant progress in cardiovascular disease (CVD) management, it remains a public health priority and a global challenge. Within the disease process, health care after a cardiovascular event (secondary prevention) is essential to prevent recurrences. Nonetheless, evidence has suggested the existence of gender disparities in CVD management, leaving women in a vulnerable situation. The objective of this study is to identify all available evidence on the existence of gender differences in health care attention after a major adverse cardiovascular event. Methods A scoping review following the structure of PRISMA-ScR was conducted. To define the inclusion criteria, we used Joanna Briggs Institute (JBI) population, concept, context framework for scoping reviews. A systematic search was performed in MEDLINE (PubMed), EMBASE and Cochrane. The methods of this review are registered in the International Platform of Registered Systematic Review and Meta-Analysis Protocols (INPLASY) (INPLASY202350084). Results The initial search retrieved 3,322 studies. 26 articles were identified manually. After the reviewing process, 93 articles were finally included. The main intervention studied was the pharmacological treatment received (n = 61, 66%), distantly followed by guideline-recommended care (n = 26, 28%) and cardiac rehabilitation (CR) referral (n = 16)”. Literature described gender differences in care and management of secondary prevention of CVD. Women were less frequently treated with guideline-recommended medications and seem more likely to be non-adherent. When analysing guideline recommendations, women were more likely to make dietary changes, however, men were more likely to increase physical activity. Studies also showed that women had lower rates of risk factor testing and cholesterol goals attainment. Female sex was associated with lower rates of cardiac rehabilitation referral and participation. Conclusions This review allowed us to compile knowledge on the existence of gender inequalities on the secondary prevention of CVD. Additional research is required to delve into various factors influencing therapeutic disparities, referral and non-participation in CR programs, among other aspects, in order to improve existing knowledge about the management and treatment of CVD in men and women. This approach is crucial to ensure the most equitable and effective attention to this issue.

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Sex Differences in Acute Coronary Syndrome: Insights From an Observation Study in Low socio-economic Cohort From India

Cited by 2 publications

References 22 publications

Clinical symptoms and ECG data in women with acute coronary syndrome

Clinical symptoms and ECG data in women with acute coronary syndrome

Gender inequalities in secondary prevention of cardiovascular disease: a scoping review

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